Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID05439	Mitoxantrone	GSE70138	ASC.C	Human	24h	10uM	EID0071

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	RELB; NFE2L3; GBX1; E2F1; TULP1; GRHL2; NFKB2; RFX1; HOXC5; ZNF467; DLX5; PRDM2; RUVBL1; PAX8; MAML3; PAX1; THRB; CIC; ATN1; ZNF556; BCL11A; ZNF711; HIPK2; MYCBP; MED15; SRCAP; ZNF154; ZNF75D; CHD3; ERCC2; SSX3; NR4A1; CIITA; ESR2; HDAC5; CDK2; ZNF219; NEUROD6; HMGB1; ZNF532; LHX3; NFIX; PRDM14; FOXJ1; ZNF224; ZNF787; NHLH1; TAF6; TP73; SLC2A4RG; HOXD3; ATOH1; SIX6; GTF3A; HOXB1; NR4A3; ACTL6A; EN2; HIVEP1; ZNF215; ARID3A; ZNF124; AES; IRF6; SRY; MYBL2; HIC2; FOXM1; PRDM12; HOXC8; CDX2; ERBB4; TCF4; ARNTL2; NR4A2; CD3D; L3MBTL1; VPS72; PRDM1; RARG; EZH2; E2F5; CBX7; REL; HOXC4; WDR77; ZNF117; TAF4B; CERS6; FOSB; OVOL2; MED12; ESRRG; DLX2; LIN28A; MYRF; GATA1; CCNE1; SIX3; SMARCB1; PPP1R13L; SOHLH2; CREBL2; CNOT3; NANOG; IRF1; DNMT1; MED14; FOXA2; ZNF107; KAT2B; ZNF264; ZNF589; SOX17; ZIC3; DLX4; KDM5C; ZBED2; CBX4; MYCL; MYBL1; ST18; HAND1; HOXB13; CALR; PSIP1; CREB3L2; ZNF652; HDAC1; ZNF611; NR3C2; EGR1; TCF21; WWC1; SMAD6; CREM; MECOM; CTNNB1; BACH2; ID1; FOXF1; NFAT5; PAWR; MEIS2; HDAC9; EHF; NR0B1; AEBP1; ARNT2; NEUROD1; HMGA1; RBBP8; EMX2; PAX6; TGFB1; JUP; DMTF1; KLF5; TFAP2A; TRIB3; ESR1; E2F2
Down-regulation	150	FHL2; NFIL3; CDK7; NRIP1; MYC; TSC22D3; USP22; FOXO3; CEBPB; CEBPD; ABL1; ZBTB11; ARID4B; XBP1; SNW1; NUP62; TRIM32; CNOT1; RLF; CEBPA; NFKBIA; DPF2; KAT7; DDIT3; SAP30; BRD8; AATF; BRD3; ADNP; PUF60; SERTAD2; ZBTB1; RNF111; TAF5; ZBTB16; BTG1; RRN3; ZNF263; ZFP36L2; MNT; TBP; SIX2; JUND; CCDC59; HOXA5; HCFC2; TCERG1; ZNF146; ATF7IP; PNRC1; MED17; CCNA2; BHLHE40; CEBPG; PDLIM1; ZNF7; NRBF2; FOXC1; VEZF1; NFIB; FOXJ3; KAT8; REST; RNF4; CTR9; KLF9; TSC22D2; NFYB; ZNF189; ELF5; ZNF281; AHR; NFE2L1; APEX1; RCOR1; ZNF12; PCGF1; AFF1; ZNF217; ZNF302; ZNF14; KLF10; DNAJC2; ZBTB7A; BCLAF1; NCOA6; FOXO1; MAGED1; PATZ1; IKBKAP; CDC5L; TOB1; COPS5; ING2; SFPQ; TAF1D; TRIM22; ASCL1; COPS2; RREB1; CARM1; CEBPZ; SIX1; PIAS1; SMAD7; PIR; KLF6; MED1; HMGB3; SMAD1; RXRA; BRD2; PHIP; HTATIP2; RYBP; TSC22D1; UBE2I; MAX; CRY1; KDM5D; ZFP36L1; ZEB2; ZNF83; FOSL1; STAT6; MBD2; BRD4; JARID2; ZMIZ1; RBPJ; SSBP2; TBL1X; EED; ERBB2; TOX3; HOXB2; NKX3-1; MAF; MAFB; WWTR1; IFI16; BASP1; CITED2; ID4; SMAD3; RUNX3; SOX9; TLE1; HOXC6; SUV39H1