Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID05203	Gsk-1059615	GSE70138	ASC.C	Human	24h	10uM	EID0070

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	HDAC6; CEBPA; TCEA2; UIMC1; UBE2B; KLF6; DDIT3; ZNF131; CENPF; PPARG; TSC22D3; FOXO4; BRD8; LHX6; ATF4; ARNTL; SOX4; PTTG1; ASXL1; HOXA5; MED16; CEBPG; TSC22D1; PKNOX1; NFE2L1; ZNF263; TAF4; TAF9; BMI1; KMT2B; NFATC1; PHIP; CEBPZ; TRPS1; PHF2; HOXC4; SNW1; TFCP2; PNRC1; HDAC5; TGIF1; MEOX2; HOXC6; HEY1; BAZ1B; TOB1; CHD1; TFAP2C; CBFB; ZNF266; FOSB; HBP1; KLF9; NR1H3; KLF5; NR1D2; SAP18; BRD3; LMCD1; MNT; TDRD3; HDAC4; HTATIP2; EZH1; ARID5A; KLF10; FOXN3; DEAF1; HOXD1; CCNA2; ZNF83; EN1; GATA3; FOXO1; TCEA1; NCOA1; ZNF189; BRD2; DNAJC2; SATB2; NKX2-2; MTA1; ZSCAN31; ZEB1; SATB1; PAWR; TCF4; CBFA2T2; TFCP2L1; HOXB7; NKX2-1; MAFB; YBX3; KLF4; CTBP2; TLE4; BASP1; CBX7; RBBP8; ELF3; EMX2; TBL1X; ELF5; ATF5; TXNIP; OSR2; AEBP1; SNAI2; RFX5; ZMYM2; CRK; EGR2; INSR; ESR1; RELB
Down-regulation	71	MYCBP; ZNF274; RUVBL1; MEIS2; SMAD6; WDR77; NFE2L3; ENO1; PRKDC; SMAD7; JUP; BHLHE40; WWC1; XBP1; MYBBP1A; WT1; VDR; NFIC; ZNF654; XRCC6; TERF1; ETS1; JAK2; SREBF1; VEZF1; SOX2; ST18; NKX3-1; C1QBP; PEG3; HDAC9; PITX1; KDM5D; BNC2; SIX6; ZNF268; AR; TCF21; NR1H4; NR2F6; MAGED1; RBBP4; ISL1; KAT2B; TOX3; MYBL1; FOSL2; CUX2; ESRRG; ZNF91; ZBED2; ZKSCAN1; LEF1; PIR; TRIM22; ZNF124; CALR; LIN28A; NEUROD1; NANOG; CREB3L2; DACH1; SALL2; NFE2; MEIS1; ERBB4; HIRA; PBX3; TRIM29; ZNF331; ZBTB18