Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID05125 Jq1-(+) GSE70138 ASC.C Human 24h 10uM EID0070
Types Number Response transcription factors
Up-regulation 51 ID2; JUN; DRAP1; TCFL5; CHD4; CENPF; SOX4; SPEN; RAN; RUVBL2; RUNX3; PPARG; IL16; ARNTL; CTR9; FOXL2; RBBP5; TRPS1; BRD2; IRF4; TLE4; FOXG1; TCF7; CITED2; POLR2A; NLK; ID3; ARID1A; TERF1; FOSB; TRIM28; NFATC1; CREB3L1; SPIB; PSIP1; CUX1; ID1; E2F5; ARID4B; HOXB6; HMBOX1; MED1; ELF3; FOXC1; LEF1; TGFB1; STAT1; DLX5; HOXB7; HOXC6; TOX3
Down-regulation 58 HLX; BRCA1; TP53; IFI16; THAP10; RBL1; RBFOX2; FOSL2; ZNF432; FOXM1; CUX2; TEAD4; ST18; TEAD3; DEK; BACH1; XRCC6; CCNA2; AHR; NR2F6; RREB1; ZBED2; CTBP1; WWTR1; ZNF232; SHOX2; TRIM22; ZNF165; YBX3; KDM5D; RBM39; TXNIP; SUB1; ZBTB38; ZNF443; NHLH2; LIN28A; BNC2; TBX3; JAK2; SALL1; TLE2; DACH1; HTATIP2; MEIS1; PLAG1; PBX3; PITX1; ZBTB16; EHF; TDP2; ZEB2; CTBP2; ISL1; ZIC3; NEUROD1; SOX11; MEIS2