Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID05108 Iox2 GSE70138 ASC.C Human 24h 3.33uM EID0070
Types Number Response transcription factors
Up-regulation 62 MTF2; MYBL2; IKZF1; TCF4; TBX2; CASZ1; NCOA3; PSMC3; DNMT3B; PLAGL1; ASH2L; TBX3; BAZ1B; GATA3; HOXA7; PRMT2; MYCL; KDM4C; ID2; ADRB2; YWHAB; POU5F1B; BCOR; PCGF2; MEOX2; TCF7; MTA1; RBBP4; KLF6; IRF4; ZKSCAN1; FOSB; TWIST1; RUNX3; CDK9; ZNF3; RBPMS; TSC22D1; TSC22D2; ZMYND8; RORA; MED6; SIX1; IL16; PRDM12; CITED2; FOXG1; NFE2L3; CD3D; PIR; TOB1; MYBL1; TLE4; FOXF1; TOX3; HLTF; ZNF281; WWTR1; HOXC6; NFE2; MYB; ATF3
Down-regulation 51 TLE1; ARID4A; CLOCK; RREB1; HOXD11; TEAD1; ZNF443; POLR3C; ZBED1; TRPS1; SKI; KLF11; NR1H3; IRF9; ZNF415; MKL2; NR0B1; EHF; NPAS2; HEY2; PGR; HMGB2; HEY1; MAGED1; JAK2; ZNF239; TCF7L1; SOX17; FOXA2; PBX1; ZNF711; NEUROD1; EMX2; SUB1; RAD21; ZNF124; PEG3; ESRRG; ESR1; ASCL1; NKX2-2; OSR2; ZIC1; SALL2; HOXD1; INSR; TXNIP; DLX5; EGR2; IRF6; LEF1