Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID05079 Gsk-461364 GSE70138 ASC.C Human 24h 0.04uM EID0070
Types Number Response transcription factors
Up-regulation 44 HIPK1; CCDC59; CENPF; PIAS2; RBL2; HCFC2; PSMC3IP; HIPK3; ZNF593; POLR2A; LOXL2; SSRP1; EZH2; ZMIZ2; TAF10; MSX1; PTTG1; ZNF217; ELK3; FOXJ1; MLXIP; CCNA2; MEF2A; PHF1; HMGB3; CRY1; TLE4; NPM1; JUND; ID3; SOX17; HOXC6; SAP30; HOXB7; BAZ1A; PIR; TSC22D2; KLF2; MYBL1; HOXC10; BASP1; HOXB2; MEIS1; ZBTB18
Down-regulation 41 CUX1; HIRA; ZKSCAN1; ZNF532; ZFY; ATF7IP; ZNF426; ZBED2; HBP1; PITX1; TDP2; BCL6; PPARGC1A; NR1H4; MAF; OVOL2; WNT4; RBFOX2; GATA6; NFE2L3; ZNF652; HOXB1; ZNF623; NR5A2; JUP; TP63; BACH1; KLF13; NR3C2; ARNT2; ESRRG; ELF1; KDM5D; ZNF91; SOX9; MAFB; PBX1; NR2F1; NR4A2; NR2F2; ZFPM2