Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID05026 Osimertinib GSE70138 ASC.C Human 24h 0.12uM EID0030
Types Number Response transcription factors
Up-regulation 16 EYA2; FOXN3; FOXO1; HEY2; TCF4; TRPS1; MAGED1; CITED2; JARID2; WWTR1; SIAH2; ZIC1; THAP11; ZFP36L1; RUNX3; ESR1
Down-regulation 16 NR1H4; MYRF; HOXD3; TOB1; SNAI2; TEAD4; TP63; HOXD1; NANOG; MYBL1; FOXF2; BHLHE41; DAXX; ARNT2; TFAP2A; TXNIP