Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04973 Ibrutinib GSE70138 ASC.C Human 24h 0.04uM EID0030
Types Number Response transcription factors
Up-regulation 20 FOXJ3; JUN; EGR1; MLXIP; C1QBP; WWTR1; EGR3; CITED2; ESR1; FOSB; HMGB3; HOXB7; EGR2; BHLHE41; NR4A1; TXNIP; MSX1; RBPMS; ATF3; HOXB2
Down-regulation 21 STAT1; PAX5; IRF9; TCF4; LEF1; SOX9; PAWR; TP63; ZNF91; HHEX; TOX; SMARCA1; LMCD1; TRIM22; SPIB; GATA6; NKX3-1; TRIM29; DAXX; ARNT2; BASP1