Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04919 Tivozanib GSE70138 ASC.C Human 24h 10uM EID0030
Types Number Response transcription factors
Up-regulation 46 MTF2; SPEN; SOX4; EGR1; KMT2A; MAFB; TRIB3; DDIT3; SATB2; DNAJC1; CEBPA; STAT5A; TFDP2; MED13; FOSB; KLF9; YAP1; RUNX1; FOXN3; PBX1; ARNTL; LMCD1; SATB1; ZNF148; ZNF93; ATF5; HOXC6; SOX2; ELF3; ZBTB16; ST18; CRY1; EYA2; ID4; THAP11; AEBP1; MITF; ID2; CREB3L2; ATF3; INSR; ZNF91; NR2F2; OSR2; LEF1; TRIM29
Down-regulation 36 ZNF274; FOSL1; BHLHE40; ING2; MYCBP; RCOR1; CITED2; KLF10; HMGB2; SF1; SUB1; SMARCA1; TGFB1; KAT2B; SIX2; SP140L; PLAGL1; TOB1; CBX4; HIPK3; SAP30; TXNIP; PITX1; HOXB6; FOSL2; BCL11B; SMAD7; GMNN; LOXL2; HLF; MYBL1; FOXF2; HOXB2; PEG3; BASP1; CREB1