Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID04906	Mitoxantrone	GSE70138	ASC.C	Human	24h	10uM	EID0029

Response Information :

Types	Number	Response transcription factors
Up-regulation	184	ZNF586; CDK2; TAF6; PAX1; MYBL2; GBX1; WDR77; ESR2; RUVBL1; PRDM12; RAX; ZNF75D; PAX3; HOXC5; PAX8; RBPJL; PDX1; ZNF154; NOC2L; CNBP; RFX1; NEUROD6; ZNF224; HOXB1; E2F1; CHD3; TAF6L; PROP1; ACTL6A; ATF6; ZBTB7B; SSX3; E2F2; NHLH1; MYCBP; E2F5; NEUROD4; SRCAP; PEX2; TFDP3; TTF2; GFI1B; CNOT3; TULP1; FOXH1; E2F4; DCC; VENTX; ZNF124; EMX1; C1QBP; HSF4; PBX2; MAML3; NR1H2; HOXD9; TBX2; HMGXB3; GRHL2; EGR1; LHX3; NRL; NR4A1; CREM; CRTC1; ZNF117; ZNF215; ZNF671; TFDP1; NEUROG1; ALX1; NFATC4; TAF9B; VGLL1; SOX5; HIPK2; ZNF444; FOXJ1; THRB; HSF1; SCAI; BARX1; POU3F2; RARG; THAP7; DNMT1; KLF15; AFF2; ENY2; TSHZ2; NFIX; ERBB4; ZNF467; ATOH1; MAK; CIITA; FEZF2; SOX18; NR5A2; ZNF532; GTF3A; ARNTL2; MXD3; SUMO1; NR4A3; SMARCB1; NR0B2; EVX1; SLC2A4RG; MED15; ZNF692; BRIP1; ZNF551; HOXD3; NR0B1; ZNF835; ZBED2; GMNN; NKX2-1; SP140L; UBTF; SOHLH2; KAT2B; AEBP1; XRCC6; HOXB13; ELK4; TCF21; NKX3-2; VDR; GLI3; HIRA; ESRRG; SRY; SKIL; PSMC3; CUX2; ZNF264; RBBP8; ZNF205; NFE2L3; NR2F1; HMGB1; ZNF652; ZNF611; NR4A2; PAWR; NR3C2; RB1; LZTS1; TDP2; SOX10; SOX2; HDAC1; FOXM1; KLF7; FOXF1; MECOM; IRF6; HDAC9; DLX2; ISL1; CREBL2; DLX5; CD3D; PRRX1; KDM5D; BACH2; BCL11A; ARNT2; TFAP2A; MEIS2; ID4; MYBL1; FOSB; CREB1; TRPS1; ID3; HOXD1; LEF1; PBX3; DAXX; EHF; NFATC3
Down-regulation	174	FHL2; CDK7; NFIL3; FOXO3; CEBPD; NFKBIA; XBP1; MYC; NUP62; FOXJ3; BHLHE40; TBP; TSC22D3; IKBKAP; FOSL1; CEBPA; CEBPB; HOXA5; SAP30; ARID4B; NCOA3; PHF20; ZNF189; DDIT3; MNT; TBPL1; ZBTB38; SSBP2; ADNP; BRD8; KAT6A; NR3C1; RLF; THAP11; CCNA2; NCOA6; SERTAD2; SCAND1; BRPF1; RNF111; ZNF263; CRK; PPRC1; SMAD1; KLF9; SNW1; ZBTB11; RNF4; KAT7; NRIP1; RREB1; DPF2; TRIM32; SOX4; ZNF292; ZMIZ1; BRD3; CTR9; DNMT3B; SPEN; KLF2; TAF5; TAF1D; KDM2A; MAGED1; IRF2; PNRC1; RBM14; TLE4; ZNF146; MED1; ZFP36L2; PDLIM1; CTCF; TSC22D1; CREB3L1; SUZ12; JARID2; CHD9; VEZF1; ZNF14; BASP1; SIX1; PLAGL2; PHIP; FOSL2; SMAD3; KMT2A; CNOT1; HSF2; ID2; NKX3-1; ZBTB7A; TLE1; MGA; SOX9; BHLHE41; MAFF; SFPQ; CEBPG; BCLAF1; ARID5B; TRIM16; CREG1; NFE2L1; DNAJC2; ZNF12; CCDC59; KAT8; SIAH2; TGIF1; AFF1; TSC22D2; ZBTB16; NRBF2; JUND; ZBTB1; ZEB2; CHD1; POLR2A; SMAD7; TBL1X; TULP4; SMARCA2; PTRF; PURA; BCL10; ZNF217; SALL1; FOXO1; TOB1; RYBP; RCOR1; PIR; ATF4; RUNX3; BANP; UBE2I; FOXC1; KLF10; TERF2; CRY1; CTBP2; ERG; FOXD1; PBX1; TOX3; KLF6; ZMYND8; NCOA1; NCOA4; VGLL4; APEX1; BTG1; BRD2; HMGN3; CHD7; AHR; NR1H3; CRYM; ABL1; HMGB3; HOXC10; KDM5A; MAFB; PUF60; HOXC6; MYB; HOXB2; MSX1; SUV39H1; USP22; TXNIP; MTF2