Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04905 Vorinostat GSE70138 ASC.C Human 24h 10uM EID0029
Types Number Response transcription factors
Up-regulation 77 RELB; TCEA2; TBPL1; KDM5B; JUN; RUVBL1; ZNF586; ID2; SOX4; HES1; RHOA; CHD4; CCNH; CRK; ZBTB40; STAT1; IKBKAP; HDAC3; NR3C2; BCL3; CTR9; ZNF226; PHF20; SETD3; HOXA10; NR4A3; RARA; SMAD6; HLTF; NR4A2; CBX7; SMARCD3; TERF1; KLF7; ID3; CHD7; HDAC1; RUNX3; ZBED2; SND1; ZKSCAN5; BBX; NR2F1; JUNB; PSIP1; NR4A1; PKNOX2; PARP1; ERF; JARID2; MXI1; TRIM24; SMAD2; SPIB; BCL10; CERS6; TRIM32; IRF4; CREM; ID1; FOSB; CREB3L2; CDK8; BACH2; MAF; HHEX; SATB2; ZNF331; DACH1; ASCL1; NR2F2; TOX; EGR3; ELK3; TBX3; MNAT1; ADRB2
Down-regulation 78 ATF5; XBP1; CEBPD; FOSL1; TP53; STAT5B; CCNA2; FOXM1; CEBPA; CEBPG; TULP3; HDGF; BAZ1A; TRIM22; DEAF1; NFYB; PITX1; PTRF; ARL2BP; YBX3; STAT6; POU5F1B; NFATC4; TAF9; AR; HMGA2; ERBB2; PPARG; SAP30; TFCP2L1; RBM39; YEATS4; SLC2A4RG; HMGB2; MSC; EN1; AES; HIPK3; BCLAF1; HOXC6; NKX3-1; FOXF2; KAT6B; TRIM29; VGLL4; ZFP36L2; ZBED1; TRIP6; STAT5A; BTG1; NCOA2; ZBTB16; TFAP2C; HOXC10; IFI16; TFEC; ZNF165; RBPMS; KDM5D; ZNF264; ESR1; ELF5; HMGA1; ZNF512B; KLF4; AEBP1; SMAD3; SOX17; HOXB7; ERG; IRF6; EHF; HOXB2; TXNIP; EMX2; MYB; SUV39H1; NFATC3