Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04865 Osimertinib GSE70138 ASC.C Human 24h 1.11uM EID0029
Types Number Response transcription factors
Up-regulation 36 SMARCD2; TERF1; HNRNPD; COPS5; FOXN3; NR0B1; TGS1; GATA2; TCEA1; SIX3; ATF4; AES; TFAP2C; NCOA2; ZNF232; GTF2I; ZHX2; POU4F1; POU2AF1; ATF3; ID3; NCOA4; VDR; TWIST1; MECOM; SOX11; BACH2; CHD7; ZFP36L2; OSR2; PCGF2; MYBL1; ZNF423; ID1; ARNT2; BASP1
Down-regulation 37 ATF5; AHR; VGLL4; NFAT5; AR; PTTG1; EGR3; FOXA2; MED23; TMF1; FOXC1; ZNF124; MAF; SUB1; TBL1XR1; INSM1; CREB3L2; FOXA1; TOX3; ZNF83; ENO1; HMGB3; SIAH2; ZBTB20; JARID2; NR2F2; ZBTB18; NR4A2; SATB2; FOSL2; NFIB; MAGED1; ASCL1; PEG3; TXNIP; EHF; NFATC3