Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04746 Vorinostat GSE70138 ASC.C Human 24h 10uM EID0028
Types Number Response transcription factors
Up-regulation 108 MEF2C; TCEA2; RUVBL1; NR3C2; SOX4; RHOA; ID2; HEY2; SNAI1; PKNOX2; TAF12; ARID1A; WWC1; WHSC1L1; SOHLH2; IRF3; CNOT3; LZTR1; NKX2-1; CHD7; HDAC1; SMARCD3; CBFA2T3; EGR3; ZSCAN9; MYF5; YBX2; ATF6; UBE2L3; ZBTB18; POU2F1; SPIB; ZNF586; SOX5; GLI3; WNT4; PAWR; SOX9; CDYL; RUVBL2; PGR; JUN; ASH2L; CREM; SND1; CBX4; SMARCB1; TCF7L2; GATAD2A; RUNX3; ARNTL; FOXA2; ANKRD1; IL16; CCNE1; ERBB4; E2F8; ENO1; TCF4; TAF4B; ZNF331; IRF8; NR5A2; NHLH2; SP110; CALR; TGFB1; NR4A3; SATB1; ZBTB20; LMCD1; MYBL1; PRKDC; JARID2; WT1; SATB2; TWIST1; BCL3; FLI1; VDR; ZNF224; SALL2; E2F5; HMGB3; ASCL1; HHEX; TRPS1; DNMT3B; CDK2; JUND; HMG20B; MXI1; MAF; NR4A1; DACH1; BHLHE41; NR4A2; PARP1; KLF6; ID3; NFATC3; TFAP2A; BCL11A; ZIC1; ZFP36L1; CITED2; PEG3; ADRB2
Down-regulation 93 CEBPD; FOSL1; CEBPA; TP53; XBP1; CCNA2; ATF5; NKX3-1; USP22; PTRF; PRMT2; VGLL4; TMF1; PHF2; NFKBIA; FOXM1; HMGA2; LEF1; RRN3; CEBPG; TRIM29; ERBB2; TRIM22; PPARG; TGFB1I1; YBX3; RNF6; SCMH1; RBM39; STAT5B; ATF1; KAT6B; SCAND1; ARL2BP; NCOA2; ZBED1; BAZ2B; FOXF2; NR1H3; NFKB1; ARID5B; PATZ1; KDM5D; UBE3A; STAT6; NR2F2; NCOA6; ADNP; MNT; RBPMS; ZBTB16; ZFP36L2; JUP; BATF3; SMAD3; APEX1; HMGB2; HDAC4; SNAI2; STAT5A; LITAF; TGIF1; PITX1; MEIS2; DDIT3; FOXD1; BCLAF1; GTF2IRD1; AEBP1; KLF2; SAP30; KLF11; HMGN3; CTNNB1; TXNIP; ZEB2; AES; SMARCA2; HMGB1; ZMYM2; BTG1; ERG; INSR; MAFB; BAZ1A; TFAP2C; MEIS1; IFI16; HOXB7; EHF; MYB; FOXF1; NR3C1