Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04742 Nvp-bgj398 GSE70138 ASC.C Human 24h 1.11uM EID0028
Types Number Response transcription factors
Up-regulation 84 KDM5B; SP2; TFAP2C; VPS72; TBX3; NR1H2; SIN3B; CCNE1; ETV4; GATA2; HSF1; CNOT3; GTF2I; MYBL2; BHLHE41; ILF2; ISL1; ATF3; FOXM1; SOX13; CSDC2; GFI1B; HBP1; MAFB; RBPMS; NPAS2; LIN28A; ZNF75D; NR5A2; MEIS2; HIC2; VGLL1; UTF1; TEAD4; TP73; BRWD1; PHOX2B; IRF7; NKX3-2; MDM4; ZNF331; RXRG; OSR2; E2F8; ZNF195; SP110; TLE2; KLF13; ZBED2; ELF5; POU2AF1; TCF7L1; PRDM1; PSMC3; DMTF1; TAF9B; TBL1XR1; DLX2; ZSCAN31; EGR3; KAT2B; PBX1; ST18; SKIL; TAL1; ZHX2; ETV5; WT1; KLF1; TRIM22; HOXB2; MEIS1; MYCL; HOXD1; SOX9; TGFB1I1; TRIB3; CALR; TSC22D1; PBX3; ARNT2; ZFPM2; ZNF423; TRIM29
Down-regulation 50 FHL2; ZNF274; PTTG1; CENPF; HMGA2; THAP11; CREB3L1; MED1; IRX5; ZNF148; NR2F2; ING2; SAP30; BRD8; HMGB2; YWHAB; SNAI2; ETS2; NPM1; YEATS4; PURA; RBPJ; ING3; CHD7; ZNF160; PSIP1; RFX5; ZBTB1; BCL11B; CBX5; CBFB; ZBTB38; ZMYND8; RBBP8; DDX5; KLF5; SIX1; ASCL1; HSBP1; HOXC6; ZNF721; TXNIP; NR1D2; SMAD1; PARP1; MAGED1; MSX1; ZIC1; MECOM; NFATC3