Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04695 Motesanib GSE70138 ASC.C Human 24h 0.37uM EID0028
Types Number Response transcription factors
Up-regulation 61 KAT6A; NUP62; BHLHE41; EGR2; NR1H2; OVOL2; CLOCK; ZNF571; ATF3; GATA6; SOX17; NR2F6; GRHL2; NRBF2; IRF1; NR1D2; ZNF184; FOSL2; PQBP1; LEF1; ID1; MED13; RXRA; HOXD11; GATA3; MYRF; KAT6B; CREB3; ZNF44; ZFPM2; SIM2; ZNF83; LPIN2; PPARG; NCOA6; ELF3; NKX2-2; PURA; MAGED1; PTRF; TFEC; ELF4; ZNF217; REPIN1; NFE2L3; TXNIP; EYA2; ID3; WT1; TCF4; ZBTB20; MXI1; PAWR; ID4; MAF; DACH1; IFI16; MECOM; PEG3; KDM5D; NFATC3
Down-regulation 47 CEBPD; CCNC; CERS6; COPS2; SIX3; HMGA1; SHOX2; PFDN5; ZNF580; C1QBP; LYL1; FOXD1; CBX6; LITAF; RBPMS; ETS1; MNDA; ZFHX4; SIX2; CHD9; TRIM22; BASP1; LOXL2; SMARCD3; HOXC10; NFIC; PAX5; SOX9; NR2F1; KLF13; TRPS1; PLAGL1; SOX2; CRYM; TFAP2C; AFF1; FOXF1; DNMT3B; MEIS2; TOX; CTBP2; ZNF721; FOXG1; ZIC1; TFAP2A; ARNT2; MYBL2