Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04667 Doramapimod GSE70138 ASC.C Human 24h 0.12uM EID0028
Types Number Response transcription factors
Up-regulation 177 E2F2; MNAT1; GRHL2; CBFA2T3; SIM2; LMCD1; ZBTB6; ZNF8; ZNF510; ZNF764; RFX2; ZNF184; SMARCC1; NKRF; PGR; EGR3; ZNF239; ZNF550; ZNF770; SOX17; ZKSCAN4; EN2; ZSCAN9; NFATC1; NR1H3; MAFF; OLIG2; CCNE1; TRIM32; ZNF711; ZNF516; TERF2; ZSCAN16; URI1; THAP10; OVOL2; SPEN; SP1; MYB; POU4F1; PRDM13; FOXA2; FOXA1; ZNF215; PRDM10; PHIP; UIMC1; SP2; NPAS2; POU4F2; EGR2; TULP2; TCF12; MAML3; CBX2; PIAS1; TFEC; THAP1; ZNF507; HIPK2; ZNF324; ZNF175; ZNF415; ERG; ILF2; ANKRD1; IRX4; SNAI1; MBD1; ZNF223; HMGXB3; ING1; AGO2; PAWR; ZNF235; ZNF180; ZNF225; ARNTL; SOX30; TAF1A; NKX2-1; RCOR1; ZNF45; ACTL6B; HIVEP2; YEATS4; OVOL1; TP63; LHX3; BANP; RERE; AFF2; NR2F6; ZNF85; ZNF281; WDHD1; NR0B1; E2F3; NKX2-2; CHD2; ELF3; CDYL; KLF3; INSR; ETS2; ZNF83; ZNF226; SOX3; GON4L; HSF2; INSM1; PIAS4; PRDM12; DLX5; SUPT6H; ITGB3BP; PPARG; PRDM2; HOXD1; IRF6; FOXJ1; WWC1; ZBTB16; ZNF573; PLAG1; CRYM; DACH1; ZNF267; ST18; MYCN; FOS; PSMC3; PITX2; FOXE1; E2F8; MYT1L; JUNB; TCF21; BAZ1A; ZKSCAN7; ZEB1; BASP1; MYCL; E2F5; ZNF512B; KDM5D; PRRX1; ZNF423; SKIL; HEY1; ZNF467; SMARCA2; RUNX3; KLF5; PAX6; BCL11A; ESR1; MYRF; MED1; BRD2; KLF10; DMTF1; IRX5; NR2F1; TSC22D1; TCF4; ZSCAN18; HTATIP2; SSX1; SOX2; TAL1; ZBTB18; ZNF721; TRIB3; HOXC6; ARNT2; NFATC3
Down-regulation 68 CALR; PA2G4; ATF2; CENPB; NRIP1; ZKSCAN1; CDK9; ERBB2; PBX2; UBP1; TRRAP; VGLL4; AFF1; ATF5; VEZF1; SMARCD3; FOSL2; STAT6; SALL1; PBX3; TADA3; TERF1; CARHSP1; MMS19; SLC2A4RG; YAP1; CITED2; TCF15; DDIT3; PCGF2; PTRF; SMARCD1; PTTG1; ZNF91; HDAC9; RBPMS; ZNF593; PPARGC1A; TGFB1; FLNA; RCOR3; ISL1; CHD9; MEF2A; ID4; DBP; TLE2; NCOA4; NR4A2; CITED1; DNAJC1; ZFP36L1; TBL1X; TCEA1; NR2F2; CTNNB1; HMGB2; DDX5; HOXC10; TRIM22; SIAH2; PITX1; MAFB; JUND; MAF; BHLHE41; SOX9; NR3C1