Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04664 Doramapimod GSE70138 ASC.C Human 24h 3.33uM EID0028
Types Number Response transcription factors
Up-regulation 45 BRCA1; TCFL5; UBP1; CCNA2; SERTAD2; CREB3L1; SMARCC1; EMX2; SOX2; ITGB3BP; FHL5; TADA3; SIAH2; FOXJ3; MTDH; PTTG1; SPIB; HDAC4; ZNF189; MYT1L; INSR; SNAI2; BHLHE41; FOSL2; NEUROD1; ZBTB18; IRF4; LEF1; ZEB2; BCL11A; EHF; BASP1; HMGB2; PAX5; MYB; TGFB1I1; TP63; HLF; EGR3; ZHX2; RBBP8; ZFPM2; PITX1; HOXC6; HEY1
Down-regulation 43 CALCOCO1; ARID5B; SMAD3; MED12; FOXC1; ZNF551; RBPJ; IRF7; SMARCC2; MEIS2; MAZ; ZNF195; THAP11; MED13; CCNE1; WT1; ETS2; STAT4; FOS; ZNF264; ELF3; CD3D; ZMYND8; ELF5; ASCL1; JUP; CITED2; HLX; TWIST1; ZNF117; MYBL1; ZMYM2; FOSB; CREB1; GATA3; TGFB1; ZNF331; ZNF652; TFAP2A; SOX9; NFATC3; MAFB; ARNT2