Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04645 Kin001-244 GSE70138 ASC.C Human 24h 10uM EID0028
Types Number Response transcription factors
Up-regulation 78 SMAD7; NPAT; GRHL2; ZNF771; ZNF267; ZNF443; IKZF1; GATA2; BATF; CREBL2; CERS6; SKI; TERF2; PRMT2; SETD3; BCL11B; FOXJ3; TFEB; RBL2; ZNF384; REL; NEDD8; MAFB; HSF1; BLM; KLF7; TRAF6; NFAT5; NR1H3; SMAD1; EMX2; CD3D; KDM5A; ZNF34; PFDN5; LDB1; IRF4; CBX7; NR3C2; ARID4A; ARNTL; JUNB; PRDM1; RYBP; THAP4; RXRA; SATB2; EYA2; MYBL2; LEF1; SIX2; CEBPZ; SMAD6; VDR; MYT1L; ZNF430; ZFP36L2; LYL1; ZBTB16; MKL2; TCF7; CTR9; KAT2B; FOXD1; HOXC10; MYCN; BCL11A; POU2AF1; TXNIP; NR1D2; HOXB7; GATA6; FOXG1; ZHX2; MAF; TAL1; KDM5D; NFATC3
Down-regulation 89 UBP1; CNOT3; PBX3; YBX3; NFKBIA; RUVBL2; KMT5A; PTRF; SHOX2; FOSB; ZEB1; NR2C1; ZNF551; WWTR1; CITED2; YAP1; HDAC1; TCF21; TRIM16; ZNF304; NR4A2; PAX6; UBE2I; ST18; FOXE1; HMGB2; ZNF587; FOXN3; CENPF; ATF4; TRIM28; CNBP; HMGN3; ZSCAN18; CEBPG; NHLH2; NAB1; SNAI2; NEUROD1; PTTG1; C1QBP; WWC1; MED24; MLXIP; GATA4; TRAK1; DLX2; ZBTB18; NKX2-2; STAT6; ZNF573; EN1; TFAP2C; RFX5; ATF3; FOXF2; INSM1; NCOA6; SOX2; TEAD1; EDF1; KLF6; CDK9; TRIP6; KLF11; PREB; KLF5; NR4A1; HEY1; ZNF83; OSR2; ID1; ZNF224; FOSL2; SOX11; YWHAB; FLI1; TRIM22; ZMYND8; ZFPM2; TOX3; FLNA; NR2F1; TGFB1; TRIM29; ZFP36L1; DAXX; TFAP2A; NR3C1