Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID04594 Xmd-885 GSE70138 ASC.C Human 24h 0.37uM EID0028
Types Number Response transcription factors
Up-regulation 72 HOXC13; TCFL5; ZNF536; DLX2; PSMC3IP; SPEN; ZNF165; GRHL2; TBX3; HTATIP2; NR0B1; CBFA2T3; IRF6; TP53; ZFP36L2; NR4A2; DEAF1; FOXC1; HIRA; AGO2; HDAC4; IRF7; WT1; TFAP2C; ZNF675; UBE2L3; TERF2; INSR; NHLH2; SOX12; CUX1; CHD7; ID1; OLIG2; TDP2; TSC22D1; DAXX; SIM2; PHF20; PBX3; OSR2; SOX9; IRX5; PAX6; GFI1B; RREB1; CTBP2; E2F5; MYCL; MXI1; NR2F1; FOXA1; EHF; EYA1; NKX3-1; HOXD1; INSM1; DNMT1; TRIM29; NR4A1; TRPS1; ZBTB16; TRIB3; ZNF331; ASCL1; FOXF2; ZNF423; BASP1; ARNT2; TFAP2A; ID3; NFATC3
Down-regulation 26 LZTS1; RERE; BMI1; CALR; MAFF; SFPQ; ELK3; ELF1; MEF2A; MEOX2; NANOG; TSC22D2; ETV5; IFI16; MITF; JARID2; EYA2; PARP1; IRF4; KDM5D; PIR; HLTF; ZEB2; TRIM16; MAFB; MECOM