Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID04522	Tnfa	GSE9055	Umbilical vein cells	Human	2.75h	10ng/ml	EID4882

Response Information :

Types	Number	Response transcription factors
Up-regulation	320	AEBP2; AGO2; AJUBA; ANKRD30A; ARID4B; ARID5A; ARNT; ARRB1; ASCL1; ATF3; ATF5; ATOH1; BARX1; BASP1; BATF2; BATF3; BCL10; BCL11B; BCL9L; BCOR; BHLHE23; BHLHE40; BHLHE41; BIRC2; BRD8; BRDT; CASZ1; CBX2; CCNC; CDK2; CDK8; CDK9; CDX1; CDYL; CEBPD; CENPF; CHD2; CHD7; CIITA; CITED4; CNOT2; CREB3; CREB3L2; CREB3L3; CRTC1; CRYM; CTBP2; CTCFL; DCC; DMRT1; DMRT2; DOT1L; E2F2; E2F5; EBF2; ELK1; ENO1; EPC1; ERBB2; ESRRB; ESX1; ETS1; EZH1; FERD3L; FIGLA; FOSB; FOXA1; FOXC2; FOXD2; FOXD3; FOXE1; FOXF1; FOXH1; FOXO4; GABPB1; GATAD2A; GBX1; GBX2; GLIS1; GRIP1; GTF2A1; GTF2A1L; HABP4; HBP1; HDAC10; HDGF; HDX; HELZ2; HES4; HES5; HEY1; HEYL; HIPK2; HIVEP1; HIVEP2; HMG20B; HMGB4; HMX1; HNF1B; HNRNPD; HOXA13; HOXB3; HOXC10; HOXC12; HOXC9; HOXD10; HR; IKZF2; ING5; INSM2; IRF1; IRF8; IRX5; JAK2; JUNB; KCNIP3; KCTD1; KDM5A; KLF14; KLF3; KLF4; KLF6; KLF9; L3MBTL4; LHX4; LHX8; LIN28A; MAEL; MAF; MAFF; MAK; MAML3; MBD1; MDM2; MEOX1; MNDA; MNT; MSC; MSX1; MYCL; MYOCD; MYT1; NAB2; NCOA7; NCOR1; NFATC1; NFE2L2; NFKB1; NFKB2; NFKBIA; NFKBIZ; NFYC; NOC2L; NPAS2; NR1I2; NR4A3; NR6A1; NRIP1; NUP62; OLIG2; OLIG3; ONECUT1; ONECUT3; OSR2; OTX1; OVOL1; PAX2; PAX4; PBRM1; PHF1; PIAS2; PITX2; POLR2A; POU2F1; POU2F2; POU3F1; POU5F2; POU6F1; PPARA; PPARGC1A; PRDM1; PRDM14; PRDM2; PRDM6; PRKDC; PROX1; PROX2; PRRX1; RARG; RAX2; RBPMS; RELA; RELB; REPIN1; RFX6; RFXAP; RHOA; RORA; RSF1; RUNX2; RYBP; SALL1; SERTAD2; SIM1; SIRT2; SIX3; SMAD3; SMAD4; SNAPC4; SOX5; SOX6; SOX9; SP100; SP140L; SP8; SPZ1; SRCAP; STAT5A; SUFU; TADA1; TAF1C; TAF4B; TAF6L; TAL2; TBL1Y; TBR1; TBX10; TBX3; TBX4; TCEA1; TCEA2; TCERG1; TEAD3; TEF; TFAP2D; TFDP2; TFE3; THRAP3; TP63; TRIM11; TSC22D1; TWIST2; UBE2B; UBTF; URI1; VDR; VGLL2; VGLL4; VSX1; WWC1; XRCC6; YBX2; ZBED2; ZBTB24; ZBTB37; ZBTB42; ZBTB47; ZEB2; ZFP1; ZFP69B; ZFY; ZIC1; ZIC3; ZIC5; ZIM3; ZMIZ2; ZNF107; ZNF160; ZNF19; ZNF214; ZNF239; ZNF254; ZNF286A; ZNF3; ZNF334; ZNF335; ZNF345; ZNF350; ZNF362; ZNF384; ZNF391; ZNF396; ZNF407; ZNF425; ZNF443; ZNF444; ZNF467; ZNF530; ZNF540; ZNF541; ZNF543; ZNF550; ZNF563; ZNF578; ZNF583; ZNF584; ZNF585B; ZNF595; ZNF597; ZNF605; ZNF611; ZNF620; ZNF625; ZNF646; ZNF664; ZNF668; ZNF671; ZNF683; ZNF688; ZNF71; ZNF749; ZNF765; ZNF771; ZNF79; ZNF836; ZNF852; ZNF99; ZSCAN10; ZXDB; ZXDC
Down-regulation	272	ABRA; AHR; ALX3; ANHX; ARID1A; ARID4A; ARX; ATF7; ATOH7; BANP; BATF; BBX; BCL6B; BCLAF1; BLZF1; BPTF; BRCA1; CBX7; CBX8; CERS3; CERS5; CLOCK; DLX4; E2F8; EBF3; EGR2; EMX2; ERBB4; ESR2; ETV1; ETV3; ETV5; FEZF2; FHL2; FIZ1; FOXA3; FOXB1; FOXC1; FOXD1; FOXJ2; FOXO1; FOXO3; FOXP2; FOXS1; FUBP1; GATA2; GATA3; GSX1; HDAC7; HES1; HES6; HIC1; HIF3A; HIPK3; HIVEP3; HLTF; HNF4G; HOXA10; HOXA11; HOXA5; HOXA6; HOXA7; HOXC8; HSF2; ID1; ID2; IKZF1; IKZF4; IL16; INSR; IRF4; KAT2B; KAT6A; KLF12; KLF15; KLF2; LCORL; LMCD1; LOXL2; LYL1; MAFB; MBD2; MECOM; MED12; MEIS3; MKL2; MLX; MLXIPL; MNX1; MTA3; MXD3; MYB; MZF1; NANOG; NCOA2; NFATC3; NFIA; NFIB; NFIC; NFX1; NOBOX; NPAS4; NR2F2; NR3C2; NR5A1; NRL; OTX2; PAX1; PAX3; PAX5; PAX8; PCGF6; PDX1; PEX14; PHF12; PHIP; PITX1; PLAG1; POU3F3; POU5F1B; PPARG; PPARGC1B; PRDM12; PRDM15; RARA; RBL2; RBPJL; RNF6; RXRG; SALL2; SAP30; SATB1; SCAI; SETD2; SIX2; SMAD6; SMAD7; SMARCB1; SNAI1; SOHLH2; SOX11; SOX14; SOX18; SOX2; SOX21; SOX3; SOX30; SPDEF; SPIB; SREBF1; SUV39H1; TADA3; TAF1; TBL1XR1; TBX1; TBX18; TBX19; TBX20; TBX21; TBX5; TCF15; TCF3; TERF2; TFAP2B; TFEB; TGIF2LY; TGS1; THAP10; THAP2; TLE1; TOX3; TP73; TRERF1; TRIM24; TRIM29; TRPS1; TSC22D2; TSC22D3; TSHZ1; TSHZ2; TTF2; TXNIP; UBE3A; USF2; VAX2; WNT4; YBX3; ZBED4; ZBED6; ZBTB12; ZBTB18; ZBTB20; ZBTB44; ZFHX3; ZFP28; ZFP90; ZHX1; ZIC2; ZKSCAN7; ZNF114; ZNF154; ZNF157; ZNF205; ZNF208; ZNF215; ZNF226; ZNF234; ZNF248; ZNF25; ZNF250; ZNF251; ZNF253; ZNF268; ZNF287; ZNF30; ZNF333; ZNF343; ZNF354C; ZNF382; ZNF431; ZNF439; ZNF44; ZNF440; ZNF441; ZNF521; ZNF529; ZNF544; ZNF548; ZNF552; ZNF554; ZNF562; ZNF568; ZNF570; ZNF594; ZNF596; ZNF599; ZNF607; ZNF613; ZNF626; ZNF627; ZNF652; ZNF653; ZNF658; ZNF660; ZNF672; ZNF680; ZNF684; ZNF696; ZNF7; ZNF700; ZNF705G; ZNF709; ZNF710; ZNF736; ZNF740; ZNF75D; ZNF76; ZNF780B; ZNF781; ZNF782; ZNF792; ZNF793; ZNF8; ZNF814; ZNF831; ZNF85; ZNF850; ZSCAN1; ZSCAN12; ZSCAN23; ZSCAN30; ZSCAN5A