Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID04516	Tnfa	GSE9055	Umbilical vein cells	Human	1.25h	10ng/ml	EID4876

Response Information :

Types	Number	Response transcription factors
Up-regulation	310	AIRE; AJUBA; ANHX; ARNT; ARNT2; ATF3; ATF5; ATF6B; ATN1; BAZ1B; BCL6; BCL9L; BCOR; BHLHE40; BHLHE41; BRD4; BRD8; CARHSP1; CBX2; CD3D; CEBPA; CEBPD; CHD2; CITED4; CNOT2; CREB3L1; CREB3L3; CRTC1; CTCFL; DLX1; DLX2; DMRT2; DMRTA1; DMRTB1; DNAJC2; DR1; E2F5; EBF2; EGR4; EHF; ELK1; EMX1; EN2; ENO1; EPC1; ERBB2; ESRRB; ESRRG; ESX1; ETS1; EZH1; FIGLA; FOSB; FOSL1; FOSL2; FOXC2; FOXD2; FOXE1; FOXF1; FOXH1; FOXL1; FOXO4; FOXR2; GATAD2A; GCM2; GLI1; GLI2; GMEB1; GRIP1; HABP4; HDAC10; HELZ2; HES5; HES7; HEY1; HEYL; HIPK2; HIVEP2; HMGB4; HMX1; HMX2; HNF4A; HNRNPD; HOXA13; HOXB13; HOXB3; HOXB8; HOXC10; HOXC4; HOXC8; HOXC9; HR; ING5; INSM1; INSM2; IRF1; IRF5; IRF6; IRX2; IRX4; JUNB; KCNIP3; KCTD1; KDM5A; KLF14; KLF3; KLF4; KLF6; KLF7; KLF8; KLF9; KMT2E; L3MBTL4; LHX1; LHX8; LIMD1; LIN28A; LITAF; LMO1; MAEL; MAF; MAFF; MBD1; MDM2; MED24; MED30; MEF2C; MEOX2; MESP1; MESP2; MITF; MKL1; MKX; MNDA; MNT; MSX1; MYBL1; MYCL; MYCN; MYNN; MYOD1; MYT1; NAB2; NCOA7; NEUROD4; NEUROG2; NFATC1; NFIX; NFKB1; NFKB2; NFKBIA; NFKBIZ; NHLH2; NPAS2; NR0B2; NR1I2; NR4A1; NR4A2; NR4A3; NR6A1; NUP62; ONECUT2; ONECUT3; OSR2; OTX1; OVOL1; PATZ1; PAX4; PCBD2; PDX1; PEG3; PHF1; PITX2; POU3F1; POU4F1; POU4F3; POU5F2; PPARD; PPARGC1A; PRDM1; PRDM10; PRDM14; PRDM15; PRDM2; PROX2; PYGO2; RAX2; RELB; REPIN1; RERE; RFX4; RFXAP; RHOA; RNF141; RORA; RSF1; RUNX3; SALL1; SALL3; SHOX2; SIM2; SIX3; SIX4; SKIL; SLC2A4RG; SMAD3; SOHLH2; SOX10; SOX13; SOX9; SP140L; SP5; SP8; SPZ1; SRY; SSX3; SUFU; SUV39H2; TADA2A; TAF4B; TAF6L; TBR1; TBX10; TCEA1; TCEA2; TCERG1; TCF21; TCF25; TEAD1; TEAD3; TFE3; THAP3; THRA; THRB; TLX1; TLX3; TRIB3; TRIM11; UBE2B; USP22; VGLL2; VHL; VSX1; WIZ; XRCC6; ZBED4; ZBTB21; ZBTB24; ZBTB40; ZBTB42; ZBTB47; ZFHX2; ZFP36L2; ZFP42; ZFP69B; ZMYM2; ZNF107; ZNF160; ZNF235; ZNF254; ZNF264; ZNF286A; ZNF3; ZNF334; ZNF335; ZNF341; ZNF345; ZNF362; ZNF366; ZNF391; ZNF416; ZNF425; ZNF429; ZNF442; ZNF443; ZNF483; ZNF484; ZNF524; ZNF530; ZNF540; ZNF541; ZNF544; ZNF547; ZNF563; ZNF572; ZNF584; ZNF585B; ZNF594; ZNF605; ZNF611; ZNF620; ZNF621; ZNF625; ZNF671; ZNF674; ZNF683; ZNF688; ZNF697; ZNF71; ZNF749; ZNF787; ZNF79; ZNF800; ZNF808; ZNF81; ZNF99; ZSCAN12; ZSCAN4; ZXDB; ZXDC
Down-regulation	255	ABRA; ALX1; ALX3; ARID1B; ARID4A; ARX; ASCL3; ASCL5; ATOH7; BANP; BATF; BATF3; BBX; BCLAF1; BLZF1; BRDT; BRIP1; CBFA2T2; CBFA2T3; CBL; CBX5; CEBPE; CECR2; CERS3; CERS5; CREBZF; CTBP2; CUX2; DBP; EED; EHMT2; ELF3; ELF5; ELK4; ELP2; ERF; ESR2; ETV3; ETV4; ETV5; FEZF2; FIZ1; FOXA1; FOXB1; FOXC1; FOXJ1; FOXL2; FOXN3; FOXO1; FOXP3; FOXP4; FOXQ1; FUBP1; GATA1; GFI1; GSC2; GSX1; GTF2A1L; GTF2IRD2; GZF1; HAND1; HIC1; HIF3A; HIRA; HIVEP3; HLF; HMGA2; HNF1A; HNF4G; HOXA10; HOXA11; HOXA5; HOXA6; HOXD11; HOXD13; HOXD4; ID1; ID2; IKZF4; ING1; JAK2; JARID2; KAT2A; KDM4C; KLF16; KMT2C; KMT2D; LCORL; LHX2; MAFG; MED23; MGA; MIXL1; MKL2; MLLT6; MLXIPL; MXD3; NACA2; NANOG; NCOA6; NEUROD1; NFATC3; NFATC4; NFYC; NOBOX; NPAS4; NR0B1; NR1H4; NR5A1; OTX2; OVOL2; PAX2; PAX5; PAX9; PBX4; PCGF3; PEX14; PHOX2A; PITX1; PML; POLR2A; POU4F2; POU6F1; PPARGC1B; PRDM16; PRKDC; PRMT2; PURA; RARA; RBPJL; RCOR3; REST; RNF6; RORB; RXRG; SAP30; SCAI; SETDB2; SIM1; SIN3A; SIRT2; SMAD7; SMAD9; SMARCA4; SNAI1; SOX11; SOX14; SOX15; SOX18; SOX2; SOX30; SOX6; SP2; SPDEF; STAT2; STAT5B; SUZ12; TADA3; TAF11; TAF1A; TBX18; TBX19; TBX20; TBX21; TBX22; TCF12; TERF2; TFAP2B; TFAP2E; TFEB; TGFB1; TGIF2LY; THAP10; THAP5; THAP6; TOX3; TSC22D1; TULP4; TWIST1; TXNIP; UBE3A; VAX2; WNT4; WWC1; ZBED6; ZBTB18; ZBTB45; ZBTB8B; ZFHX4; ZFP28; ZFP3; ZFP36L1; ZFP64; ZFPM1; ZGLP1; ZHX3; ZKSCAN5; ZKSCAN7; ZNF100; ZNF101; ZNF124; ZNF141; ZNF154; ZNF17; ZNF215; ZNF226; ZNF233; ZNF234; ZNF248; ZNF250; ZNF28; ZNF333; ZNF33B; ZNF354C; ZNF382; ZNF398; ZNF408; ZNF41; ZNF415; ZNF417; ZNF420; ZNF439; ZNF473; ZNF490; ZNF496; ZNF536; ZNF554; ZNF562; ZNF575; ZNF577; ZNF579; ZNF585A; ZNF589; ZNF599; ZNF613; ZNF627; ZNF653; ZNF667; ZNF672; ZNF684; ZNF687; ZNF692; ZNF696; ZNF7; ZNF710; ZNF74; ZNF770; ZNF777; ZNF783; ZNF789; ZNF792; ZNF80; ZNF85; ZNF92; ZSCAN23