Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID04292	Triptolide	GSE28502	Umbilical vein smooth muscle cells	Human	24h	NA	EID4652

Response Information :

Types	Number	Response transcription factors
Up-regulation	456	ABRA; AES; AFF3; AIRE; ALX1; ALX4; ANHX; ANKRD30A; ARID1B; ARID5A; ARRB1; ARX; ASCL1; ASCL2; ASCL3; ASCL5; ATF3; ATF5; ATF6; ATF6B; ATN1; ATOH1; ATOH7; BACH2; BARHL1; BARX2; BATF; BCL6B; BHLHE22; BHLHE23; BRD3; BRD4; BRDT; BTF3; CALR; CAMTA1; CASZ1; CBFA2T3; CBX2; CD3D; CDX2; CEBPA; CEBPE; CERS3; CERS5; CERS6; CHD3; CIITA; CITED1; CREG1; CRX; CSDE1; CTCFL; CUX1; CUX2; DACH2; DCC; DLX6; DMRT1; DMRT3; DMRTC2; DRAP1; DTX1; E2F1; E2F2; EBF1; EBF2; EBF3; EBF4; EDF1; EGR3; EGR4; EHMT2; ELF3; ELF5; EMX1; EN2; ENY2; EP400; EPAS1; ERBB2; ESR1; ESR2; ESRRB; ESRRG; ESX1; ETV3; ETV7; EVX1; EWSR1; FEV; FEZF2; FHL5; FOS; FOSB; FOXA1; FOXA3; FOXD2; FOXF2; FOXH1; FOXL1; FOXN1; FOXN4; FOXO6; FOXP2; FOXP3; FOXP4; FOXR2; GATA4; GATA5; GATA6; GCM1; GFI1B; GLI4; GRHL1; GSX1; GTF2IRD2B; HCFC1; HDAC1; HDAC10; HDAC11; HDAC6; HDAC9; HELZ2; HES2; HES5; HESX1; HIC2; HIF3A; HIPK3; HIVEP1; HLF; HMG20B; HMGA1; HMX1; HMX2; HNF1A; HNF1B; HNF4A; HOXB1; HOXB8; HOXC12; HOXD1; HOXD13; HOXD4; HOXD9; HSBP1; HSF4; IKZF1; IKZF3; IKZF4; IL16; IL31RA; INSM2; INSR; IRF4; IRF5; IRX1; IRX2; IRX4; IRX5; ISX; KAT2B; KCNIP3; KCTD1; KLF1; KLF14; KLF15; KLF8; KMT2B; L3MBTL1; L3MBTL4; LEF1; LHX1; LHX3; LHX4; LHX6; LHX9; LIMD1; LIN28B; LMX1A; LMX1B; LOXL2; MAEL; MAF; MAFB; MAK; MAPK8IP1; MBD3; MED12; MED24; MEOX2; MESP1; MIXL1; MKX; MLLT6; MLXIPL; MNDA; MNX1; MSX2; MYCL; MYCN; MYF5; MYNN; MYRF; MYRFL; MYT1L; NACA2; NANOG; NEDD8; NEUROD1; NEUROD2; NEUROG2; NEUROG3; NFE2L1; NFE2L3; NFKBIB; NFRKB; NHLH1; NHLH2; NPAS1; NPAS4; NPM1; NR1I2; NR1I3; NR2E1; NR4A1; NR4A2; NR5A1; NR5A2; NR6A1; OLIG2; ONECUT1; ONECUT2; OTX1; OVOL2; PAX1; PAX2; PAX3; PAX5; PAX6; PAX7; PAX8; PAX9; PBXIP1; PDX1; PFDN5; PHF8; PHOX2A; PKNOX2; PLAGL1; POLR2A; POU3F1; POU3F3; POU4F1; PPARD; PPARG; PPARGC1A; PPARGC1B; PRDM6; PROP1; PROX1; PRRX2; PSPC1; PURB; PYGO2; RARG; RAX; RAX2; RBPJL; RBPMS; RCOR1; RFX4; RFX6; RHOA; RIPK3; RNF141; RNF6; RORA; RORB; RORC; RUNX3; SALL3; SAP30; SCRT1; SFMBT1; SHOX2; SIM1; SIM2; SIX1; SIX2; SIX3; SIX4; SIX5; SNAI1; SOHLH1; SOHLH2; SOX1; SOX13; SOX21; SOX3; SOX7; SOX8; SP2; SP5; SP6; SP7; SP8; SPI1; SPIB; SPIC; SPZ1; SRCAP; SREBF2; SRY; SSX1; SSX3; ST18; STAT2; SUFU; SUMO1; TADA2A; TAF10; TAF6L; TAL1; TAL2; TBX1; TBX10; TBX20; TBX5; TCEA1; TCEA2; TCEB2; TCF21; TCF24; TCF25; TCF3; TCFL5; TEAD2; TEF; TFAP2B; TFAP2C; TFCP2L1; TFDP1; TFDP3; TFE3; TGFB1; TGIF2LY; TGS1; THAP2; THRA; TLX1; TLX2; TONSL; TOX3; TP63; TRIM29; TSC22D1; TSC22D2; TSC22D3; TUB; TULP1; TULP2; URI1; USF1; USF2; UTF1; VENTX; VGLL1; VSX1; WNT4; WT1; WWC1; XRCC6; YBX1; YBX2; YWHAB; ZBTB12; ZBTB16; ZBTB44; ZBTB7C; ZFP1; ZFP2; ZFP28; ZFP36L2; ZFP42; ZGLP1; ZIC1; ZIC3; ZIC4; ZNF135; ZNF154; ZNF160; ZNF169; ZNF17; ZNF214; ZNF219; ZNF233; ZNF257; ZNF28; ZNF286A; ZNF33A; ZNF366; ZNF384; ZNF391; ZNF396; ZNF415; ZNF417; ZNF423; ZNF425; ZNF429; ZNF467; ZNF488; ZNF491; ZNF527; ZNF541; ZNF543; ZNF546; ZNF550; ZNF555; ZNF572; ZNF577; ZNF580; ZNF585A; ZNF585B; ZNF594; ZNF610; ZNF620; ZNF625; ZNF626; ZNF630; ZNF646; ZNF653; ZNF674; ZNF681; ZNF682; ZNF688; ZNF709; ZNF713; ZNF721; ZNF732; ZNF740; ZNF763; ZNF771; ZNF777; ZNF781; ZNF789; ZNF814; ZNF831; ZNF837; ZNF844; ZNF865; ZNF99; ZSCAN1; ZSCAN30; ZSCAN4
Down-regulation	897	ABL1; ABT1; ADNP; ADNP2; ADRB2; AEBP2; AFF1; AFF4; AGO2; AJUBA; APEX1; AR; ARHGAP35; ARID1A; ARID2; ARID4A; ARID4B; ARID5B; ARNT; ARNT2; ASXL1; ATF1; ATF2; ATF4; ATF7; ATF7IP; ATOH8; ATXN7L3; BACH1; BATF2; BAZ1A; BAZ1B; BAZ2A; BAZ2B; BBX; BCL10; BCL11A; BCL11B; BCL9L; BCLAF1; BCOR; BDP1; BHLHE40; BHLHE41; BLM; BLZF1; BNC1; BNC2; BPTF; BRCA1; BRCA2; BRD7; BRD8; BRF2; BRIP1; BRWD1; BTG1; CAPN15; CARHSP1; CBFA2T2; CBFB; CBL; CBX3; CBX5; CBX6; CBX8; CCAR1; CCDC59; CCNA2; CCNE1; CCNT1; CDC5L; CDK7; CDK8; CDK9; CDYL; CEBPD; CEBPZ; CECR2; CENPB; CENPF; CHD1; CHD6; CHD7; CHD8; CHD9; CITED2; CITED4; CLOCK; CNOT1; CNOT2; CNOT6; CREB1; CREB3L1; CREB3L2; CREBZF; CREM; CRK; CTBP2; CTCF; CTNNB1; CXXC1; DACH1; DDX17; DDX20; DLX1; DMRT2; DMRTA1; DNAJC2; DNMT3B; DOT1L; DPF2; DR1; DYRK1B; E2F3; E2F4; E2F5; E2F6; E2F7; E2F8; E4F1; EED; EGR1; EHMT1; ELF1; ELF2; ELF4; ELK4; ELP2; EMX2; ENO1; EOMES; EP300; EPC1; EPC2; ERBB4; ERCC3; ERF; ERG; ESRRA; ETS1; ETS2; ETV1; ETV5; ETV6; EYA2; EZH1; FHL2; FLI1; FOSL1; FOSL2; FOXA2; FOXC2; FOXD1; FOXF1; FOXG1; FOXJ1; FOXJ3; FOXK1; FOXK2; FOXL2; FOXN2; FOXN3; FOXO3; FOXO4; FOXP1; FUBP1; GABPB1; GATA2; GATAD2A; GATAD2B; GCM2; GLI2; GLI3; GLIS2; GMEB1; GMEB2; GMNN; GON4L; GRIP1; GSC2; GTF2A1; GTF2I; GTF2IRD1; HABP4; HAND2; HBP1; HCFC2; HDAC4; HDAC7; HDX; HEY2; HHEX; HIC1; HINFP; HIPK1; HIPK2; HIRA; HIVEP2; HIVEP3; HKR1; HLX; HMBOX1; HMG20A; HMGA2; HMGB2; HMGB3; HMGB4; HMGXB3; HMGXB4; HNRNPD; HOXA1; HOXA10; HOXA11; HOXA13; HOXA2; HOXA3; HOXA4; HOXA6; HOXB2; HOXB4; HOXB6; HOXB7; HOXC11; HOXC5; HOXC6; HOXC8; HOXC9; HOXD10; HOXD11; HSF2; ID1; ID2; ID3; ID4; IFI16; IKZF2; IKZF5; ING1; ING3; ING4; ING5; IRF2; IRF6; IRF8; IRX3; ISL1; ISL2; JAK2; JARID2; JAZF1; JDP2; JMY; JUN; JUND; KAT5; KAT6A; KAT6B; KAT7; KAT8; KDM2A; KDM2B; KDM4A; KDM5A; KDM5B; KLF12; KLF13; KLF16; KLF2; KLF3; KLF6; KLF7; KLF9; KMT2A; KMT2C; KMT2D; KMT2E; L3MBTL2; LCORL; LHX2; LIN54; LPIN2; LYL1; MAML2; MAML3; MAX; MAZ; MBD2; MBD4; MDM2; MDM4; MECOM; MECP2; MED1; MED10; MED13; MED14; MED17; MED20; MED23; MED25; MED26; MED27; MED31; MED4; MED6; MED7; MEF2A; MEF2C; MEIS1; MEIS2; MEN1; MEOX1; MGA; MIER3; MITF; MKL1; MKL2; MLLT10; MLX; MLXIP; MMS19; MNT; MSC; MTA3; MTDH; MTF1; MTF2; MYB; MYBL2; MYC; MYOCD; MYSM1; MZF1; NAB1; NAB2; NCOA2; NCOA3; NCOA6; NCOA7; NCOR1; NCOR2; NEUROG1; NFATC1; NFATC2; NFATC3; NFE2L2; NFIA; NFIB; NFIX; NFKBIA; NFKBIZ; NFX1; NFXL1; NFYA; NFYB; NLK; NPAS2; NPAT; NR0B1; NR1H4; NR2C1; NR2C2; NR2F1; NR2F2; NR2F6; NR3C1; NRBF2; NRF1; NRIP1; NSD1; NUP62; ORC2; OSR1; OTX2; OVOL1; PATZ1; PAWR; PAX4; PAXBP1; PBRM1; PBX1; PBX2; PBX3; PCGF1; PCGF3; PCGF5; PCGF6; PEX14; PEX2; PHF12; PHF2; PHF20; PHIP; PIAS1; PIAS2; PIAS4; PITX1; PITX2; PKNOX1; PLAG1; PLAGL2; PML; PMS1; PNRC1; PNRC2; POLR3C; POLR3F; POU2F2; POU2F3; POU5F2; PPARA; PPRC1; PRDM1; PRDM10; PRDM15; PRDM16; PRDM2; PRDM4; PRDM5; PRDM9; PREB; PRKDC; PRMT2; PRRX1; PUF60; PURA; RAD21; RAN; RARA; RARB; RBAK; RBBP4; RBL1; RBL2; RBM14; RBM39; RBPJ; RCOR2; RCOR3; REL; REPIN1; RERE; REST; RFC1; RFX2; RFX7; RFXANK; RFXAP; RLF; RLIM; RNF138; RNF14; RNF4; RREB1; RRN3; RSF1; RUNX2; RXRA; RXRB; RYBP; SAFB; SALL2; SAP130; SATB1; SATB2; SCAI; SERTAD2; SETD2; SETD7; SETDB1; SETDB2; SF1; SFPQ; SIAH2; SIN3A; SKI; SKIL; SLC2A4RG; SMAD1; SMAD2; SMAD3; SMAD4; SMAD5; SMAD6; SMAD7; SMAD9; SMARCA2; SMARCA5; SMARCAD1; SMARCB1; SNAI2; SNIP1; SNW1; SOX11; SOX17; SOX2; SOX4; SOX5; SOX6; SOX9; SP1; SP100; SP110; SP140L; SP3; SPDEF; SPEN; SREBF1; SRF; SSBP2; SSBP3; STAT5B; SUB1; SUPT6H; SUPT7L; SUV39H1; SUV39H2; SUZ12; TADA1; TADA2B; TADA3; TAF11; TAF4; TAF5; TAF5L; TAF7; TAF9B; TBL1X; TBL1XR1; TBP; TBPL1; TBR1; TBX15; TBX18; TBX2; TBX22; TBX3; TBX6; TCERG1; TCF12; TCF19; TCF4; TCF7L1; TCF7L2; TDP2; TDRD3; TEAD1; TEAD4; TERF2; TFAM; TFAP2A; TFCP2; TFEB; TFEC; TGIF1; THAP11; THAP3; THAP4; THAP5; THAP6; THRAP3; THRB; TLE1; TLE4; TLX3; TMF1; TOPORS; TOX; TOX2; TOX4; TP73; TRAF6; TRAK1; TRERF1; TRIM11; TRIM16; TRIM24; TRIM27; TRIM32; TRIM33; TRIP11; TRIP4; TRPS1; TRRAP; TSHZ1; TSHZ2; TSHZ3; TTF1; TULP3; TULP4; TWIST1; TWIST2; TXNIP; UBE2B; UBE2I; UBE3A; UBP1; UBTF; USP16; USP21; USP22; VDR; VEZF1; VGLL4; VHL; VPS25; WDHD1; WDR5; WHSC1; WHSC1L1; WIZ; WWP1; WWTR1; XBP1; YBX3; YEATS4; YY1; ZBED1; ZBED4; ZBTB1; ZBTB11; ZBTB18; ZBTB2; ZBTB20; ZBTB21; ZBTB24; ZBTB26; ZBTB37; ZBTB38; ZBTB4; ZBTB40; ZBTB41; ZBTB42; ZBTB43; ZBTB45; ZBTB47; ZBTB6; ZBTB7A; ZBTB7B; ZFHX3; ZFHX4; ZFP14; ZFP36L1; ZFP37; ZFP41; ZFP62; ZFP64; ZFP69; ZFP69B; ZFP90; ZFP91; ZFP92; ZFPM2; ZFX; ZFY; ZHX1; ZHX2; ZHX3; ZIK1; ZIM3; ZKSCAN3; ZKSCAN4; ZKSCAN7; ZMIZ1; ZMYM2; ZMYND8; ZNF10; ZNF100; ZNF101; ZNF107; ZNF112; ZNF114; ZNF12; ZNF121; ZNF133; ZNF134; ZNF138; ZNF141; ZNF142; ZNF146; ZNF148; ZNF165; ZNF174; ZNF175; ZNF18; ZNF180; ZNF184; ZNF195; ZNF197; ZNF200; ZNF202; ZNF208; ZNF215; ZNF217; ZNF22; ZNF221; ZNF222; ZNF223; ZNF224; ZNF225; ZNF226; ZNF227; ZNF229; ZNF230; ZNF236; ZNF24; ZNF248; ZNF250; ZNF251; ZNF254; ZNF26; ZNF260; ZNF264; ZNF266; ZNF267; ZNF273; ZNF275; ZNF281; ZNF283; ZNF284; ZNF287; ZNF292; ZNF3; ZNF30; ZNF302; ZNF304; ZNF317; ZNF320; ZNF322; ZNF329; ZNF333; ZNF335; ZNF33B; ZNF341; ZNF343; ZNF347; ZNF350; ZNF354C; ZNF362; ZNF367; ZNF383; ZNF394; ZNF397; ZNF398; ZNF407; ZNF41; ZNF416; ZNF43; ZNF430; ZNF431; ZNF436; ZNF439; ZNF44; ZNF443; ZNF444; ZNF445; ZNF446; ZNF449; ZNF45; ZNF460; ZNF468; ZNF469; ZNF470; ZNF471; ZNF483; ZNF485; ZNF492; ZNF493; ZNF496; ZNF502; ZNF506; ZNF507; ZNF512; ZNF512B; ZNF519; ZNF521; ZNF524; ZNF526; ZNF529; ZNF530; ZNF536; ZNF540; ZNF547; ZNF548; ZNF549; ZNF551; ZNF552; ZNF557; ZNF559; ZNF562; ZNF564; ZNF566; ZNF567; ZNF568; ZNF569; ZNF570; ZNF571; ZNF573; ZNF574; ZNF576; ZNF579; ZNF581; ZNF583; ZNF584; ZNF586; ZNF587; ZNF587B; ZNF593; ZNF597; ZNF599; ZNF605; ZNF606; ZNF614; ZNF616; ZNF618; ZNF619; ZNF623; ZNF624; ZNF629; ZNF639; ZNF641; ZNF649; ZNF652; ZNF654; ZNF658; ZNF662; ZNF665; ZNF667; ZNF668; ZNF672; ZNF675; ZNF677; ZNF678; ZNF680; ZNF684; ZNF687; ZNF689; ZNF691; ZNF696; ZNF697; ZNF7; ZNF70; ZNF700; ZNF701; ZNF708; ZNF71; ZNF710; ZNF711; ZNF736; ZNF74; ZNF746; ZNF747; ZNF749; ZNF764; ZNF765; ZNF766; ZNF770; ZNF775; ZNF776; ZNF780A; ZNF780B; ZNF782; ZNF783; ZNF786; ZNF79; ZNF791; ZNF792; ZNF793; ZNF8; ZNF800; ZNF805; ZNF81; ZNF823; ZNF827; ZNF829; ZNF83; ZNF84; ZNF85; ZNF850; ZNF852; ZNF879; ZNF880; ZNF891; ZNF91; ZNF92; ZNF93; ZSCAN12; ZSCAN18; ZSCAN2; ZSCAN23; ZSCAN25; ZSCAN9; ZXDA; ZXDB; ZXDC; ZZZ3