Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID03882 Celastrol GSE119281 NPCs Human 6h NA EID4385
Types Number Response transcription factors
Up-regulation 60 ATF3; NR4A3; NR4A2; HBP1; FOS; AGO2; SIX1; EGR1; HTATIP2; MEF2A; TSC22D2; HIVEP1; KLF2; NR4A1; MAFF; SERTAD2; NFIL3; UBE2B; PIR; CEBPB; BCL6; TBX3; FOSB; ATF4; ARID4B; BANP; CREM; MED13; KLF4; TGIF1; BTG1; EGR3; JUNB; MAFG; MYC; FOSL1; ARID5B; PAWR; NR1D2; TBL1XR1; ZNF274; ATF5; ZBTB38; KLF9; SMAD3; CEBPG; TRIB3; TSC22D3; FOSL2; MAFB; TOB1; TCF7L2; NRIP1; EPAS1; FHL2; MEF2C; POU2AF1; GATA6; YBX3; TSC22D1
Down-regulation 18 CCNA2; DNMT3B; ZFP36L2; ASH2L; GMNN; SALL2; ZMYND11; MNDA; SMARCD3; FOXM1; SUB1; TFDP1; SUV39H1; HLTF; CENPF; PLAGL1; TCFL5; CBX5