Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID01457	Maprotiline	GSE59905	Heart	Rat	120h	380mg/kg	EID1954

Response Information :

Types	Number	Response transcription factors
Up-regulation	58	CTBP2; WDR5; EYA2; ERBB2; CDK7; RXRB; BIRC2; POU1F1; NR1H2; NAB1; STAT1; UBTF; THRA; JUNB; JAK2; MAFB; ZNF655; PLRG1; NR2F6; ZFP91; RBL2; ZNF22; NCOA2; ZNF180; RERE; NR2C2; RUVBL1; CRYM; DNMT1; CHD4; NFYB; SMAD1; DEK; NR1H3; SMAD5; SSBP3; NR1D2; CTBP1; POU2F1; KLF15; TEF; CEBPA; ATF2; RARB; SMARCA4; NEUROD1; NFYC; ZNF597; DCC; BCL11A; WT1; PLAGL1; KLF5; CCNH; ERBB4; CCNC; WNT4; FOXA2
Down-regulation	54	FOS; CD3D; NR2F2; RAX; CCNA2; EGR2; ATF3; ZNF260; PCGF6; RAB24; TXNIP; BARHL1; GATA1; E2F5; EGR1; HR; FOXM1; ASCL2; MTA2; ST18; PBX2; ESR2; CHD3; NR0B2; JUND; CDK9; MYC; ID4; CREB3L1; REST; SIX1; MSX2; SHOX2; OLIG1; KLF4; NR0B1; LZTS1; EGR4; STAT5A; DBP; THRB; HES1; NR1H4; PEX2; MEOX2; CCNE1; MYF6; FOXA1; CTNNB1; RIPK3; HES5; CITED4; ING4; RHOA