Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00715	Lansoprazole	GSE57805	Hepatocyte	Rat	24h	240uM	EID1208

Response Information :

Types	Number	Response transcription factors
Up-regulation	123	MDM4; ESRRA; BTAF1; SUPT3H; DOT1L; HTATIP2; ZNF746; MAFK; LIN54; MAFG; SCMH1; KLF5; NR4A2; PRDM2; FOXK1; BLM; PSMD9; NUP62; GMNN; FOSL1; MED30; TAF12; DNAJC2; MEF2D; ATF4; FOXJ2; TAF6L; ATF3; TCEA2; KLF4; HSF1; MLX; YBX3; TRIB3; PKNOX1; ZNF787; DDIT3; AGO2; MBD1; PIR; SUV39H2; SUFU; WWP1; POLR2A; KDM5A; FOSL2; GPS2; MECP2; BHLHA15; KLF15; NSD1; BIRC2; MDM2; SIRT2; ATF6; CARM1; FOXK2; ZNF672; THAP7; ATF7IP; MAFF; NRF1; ZNF143; MED6; RTEL1; ZNF226; PIAS2; ARID3B; TFCP2; GTF2A1; MED13; CCNC; TOPORS; CREG1; PSMC3IP; ZMYND11; TDRD3; USF2; AATF; HIPK3; TCEA1; HDAC4; AFF4; ZNF593; SETD5; PPP1R13L; POLR3C; KLF9; RIPK3; FOXN2; TFE3; ATF6B; AHR; GATAD2B; BRF2; SREBF1; CLOCK; MAZ; PRDM4; EZH1; ZFPM1; ZNF655; ZBTB7B; CRY1; YY1; UBP1; CEBPB; SMARCA4; TAF5; RORA; SMAD4; ZNF592; MEN1; NR1D2; ITGB3BP; PSPC1; ZNF367; IRF2; UBTF; RXRA; RING1; CEBPA; ATF2
Down-regulation	147	UBE2I; IRF6; RFX5; ZNF22; CRYM; KDM5C; GTF2I; ZMIZ1; ONECUT1; MAGED1; RBPMS; CNOT6; MYRF; ZNF266; SMARCA2; NR2F2; JUN; KLF12; MYCBP; HHEX; AJUBA; ONECUT2; ZFHX4; TSC22D3; PCBD1; LPIN2; NFIB; VEZF1; RARB; TSC22D1; ZNF467; PAWR; NR1H4; SSBP3; HCFC1; NFIA; NONO; CBX2; VGLL4; YWHAB; ZNF532; SMARCE1; CITED2; PML; ETS1; SP110; SOX13; SUB1; CREB5; TFCP2L1; NFKB1; ZNF260; UBE2K; ZBTB4; ZNF629; TCF7L1; C11orf95; JARID2; PHF12; AFF1; DAXX; NCOA7; ZNF148; TEAD2; ZHX1; RXRG; NFAT5; CARHSP1; KLF10; TRIM32; RNF141; ZNF512B; RBBP8; MEIS1; IRF1; ZZZ3; ASH2L; ARHGAP35; ESRRG; TLE2; PIAS1; CDIP1; SKIL; JUP; CHD6; ANKRD1; CUX1; SOX6; PCGF2; ZFP57; CNOT2; CBX6; PDLIM1; ZBTB8A; ZHX2; HDAC2; ZNF697; RELB; KMT2D; MAFB; HIPK2; SSBP2; NPAS2; ZNF354A; RFX3; ZBTB45; ELK4; ZNF710; IRF7; PATZ1; ID4; LMCD1; ZMYM2; ZKSCAN1; ZNF358; GLIS2; TCF7L2; CEBPD; TEAD4; MAPK8IP1; ZBTB47; BHLHE41; LOXL2; ZBTB20; GABPA; NCOA4; ZFP90; NFATC1; ZNF517; EZH2; DEK; TXNIP; NFYB; TCF4; STAT3; PBX2; SMAD7; GATA6; MECOM; DBP; NR1D1; CHD7; IRF9; MAF; BCL6B; ELK3; FOXA3