Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00713	Labetalol	GSE57805	Hepatocyte	Rat	24h	250uM	EID1206

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	KLF5; BHLHA15; MAX; ATF4; MNT; NUP62; ATF3; APEX1; KLF4; PPRC1; TRIB3; BIRC2; TAF6L; DDIT3; CDYL; VHL; ZNF787; DOT1L; MAFK; BTG1; BCOR; HBP1; AATF; MYC; MDM4; MLXIP; SIRT2; RUNX1; ZNF800; TSG101; FOXN2; ZNF236; HINFP; DNAJC2; AGO2; ZNF142; MED12; JAK2; ZNF180; TOPORS; GRHL1; RIPK3; RBPJ; RB1; YBX3; ZEB2; SMAD3; ZNF367; CHD1; KLF15; TAF1D; ATF6; SIAH2; CEBPD; SETD5; ATF6B; FOSL2; TSC22D2; MAFG; FOXK2; HSF1; MITF; E2F5; MAZ; HIPK3; LIN54; KLF13; CERS6; MAFF; ZBTB34; IRX2; ZNF593; KLF3; ZNF655; CRY1; JUNB; MAF; FOSL1; CEBPB; USF2; ID1; ZNF131; MDM2; KAT6A; TCEA1; ATF7IP; RARG; KLF6; CCNC; EGR2; MGA; PRDM4
Down-regulation	70	HHEX; RFX5; CRYM; IRF6; SMARCA2; TCF7L2; NR5A2; HNF4A; JUN; LPIN2; NFIA; PML; SP110; CREB3L3; GTF2I; ZNF22; MEIS1; NR1I2; NFIB; PCBD1; MYRF; MAGED1; PIR; JARID2; ZFHX4; ZBTB20; NR3C2; ESRRG; TFCP2L1; AJUBA; NCOA4; ZNF148; ONECUT2; IRF1; IRF7; ZNF532; ONECUT1; HDAC11; SMARCD3; SUB1; RXRG; SOX6; CHD6; RARB; MXI1; ZNF266; NFIC; ZNF697; SMARCE1; ZKSCAN1; HELZ2; YEATS2; PATZ1; DBP; RBPMS; UBE2K; MAFB; PSPC1; STAT1; NR2F2; HIPK2; KLF12; TEAD4; LMCD1; NR1I3; TEF; LOXL2; FOXA3; C11orf95; MAPK8IP1