Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00708	Ketoconazole	GSE57805	Hepatocyte	Rat	16h	90uM	EID1201

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	KLF5; MYC; EPC1; ZNF639; BIRC2; ATF3; ZEB1; FOXN2; GMEB2; ZNF142; GRHL1; PPRC1; TAF1C; TRIB3; MDM4; KLF4; APEX1; ATF4; PCGF1; TSC22D2; AATF; MAFK; FOSL2; KAT5; BANP; MDM2; KLF15; CDYL; ZNF655; CEBPG; RUNX1; SCMH1; UBE3A; FOXK2; HBP1; SMAD2; REPIN1; MED13; MAFG; MNT; PPARG; ORC2; MEF2A; HINFP; ZBTB2; KLF6; ZNF236; DDIT3; MECP2; ATF1; TAF5; NFYA; GATAD2B; PRDM1; BLM; E2F5; RNF4; BTAF1; ZNF513; NUP62; SUV39H2; ZNF180; PKNOX1; DNAJC2; ATF6; IRX2; TFCP2; ZFP91; MAX; ZNF592; AFF4; MIER3; CLOCK; ZZZ3; KLF16; DOT1L; PCGF5; CCNH; ZNF202; BAZ1A; MAFF; LIN54; NFIL3; MYBL1; NSD1; CERS6; ZNF131; GPS2; MED30; CRY1; NR1D2; HSF1; ZNF34; EHF; RSF1; FOSL1; RNF111; IKZF5; RBPJ; ING3; NFKBIB; ATF7IP; PNRC2; FOXK1; CHD2; CEBPB; CCNC; MGA; PRDM4; YBX3; UBTF; MED1; HDAC4; TDRD3; SMAD4; ATF2; SP1; BHLHE40; JAK2; ZNF367; MYSM1; MITF; TFE3; ZNF593; URI1; NR1D1; UBP1; HIPK3; ZNF597; TAF1D; CEBPD; INSR; ILF2; USF2
Down-regulation	102	HHEX; NFIB; NR5A2; BCL3; MYRF; SFPQ; HDAC5; HNF4A; ZMIZ1; LPIN2; NFIA; PCBD1; ONECUT1; RBL2; ZBTB20; TRIM32; SMARCA2; ZBTB4; MXI1; RFX5; AJUBA; CNOT6; BCL9L; TBL1XR1; MEIS1; IRF1; GTF2I; ZNF467; ZNF32; YWHAB; PHF12; MAGED1; SP110; RXRG; JARID2; TCF7L1; YEATS2; ZFHX4; UBE2I; FOXA2; GATA6; KLF12; TCF7L2; VGLL4; ZNF22; ZNF266; TSC22D1; CBX2; KDM5B; PML; KDM5C; NCOA4; NR2F2; SMARCE1; NCOR2; GATA4; KMT2A; SOX6; PDLIM1; SREBF2; ONECUT2; ZNF512B; RARB; ZNF322; PBX2; KMT2D; SALL1; HMG20A; HELZ2; TBL1Y; ZHX1; RBPMS; LDB1; ZMIZ2; NFATC2; FOXP4; ZBTB38; NR1H4; TSC22D3; SSBP3; ZMYND8; CRYM; ZBTB8A; ZNF226; ZBTB45; ZNF517; TEAD2; TCF3; C11orf95; ZNF260; PATZ1; NFKB2; ESRRG; HIPK2; GLIS2; FLNA; MAFB; CREB5; TXNIP; REXO4; TRIM16; ANKRD1