Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00707	Isotretinoin	GSE57805	Hepatocyte	Rat	24h	500uM	EID1200

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	NR0B2; BHLHA15; ZNF142; ZNF391; MAFK; ATF3; ATF4; ZNF180; MAX; KLF15; GRHL1; ARID3A; NUP62; PHF1; HTATIP2; ZNF746; MLX; PPARG; KLF5; TRIB3; HCFC2; LIN54; HINFP; KLF9; MAFG; TAF6L; EPC1; FOSL1; DDIT3; MED13; ZXDC; PA2G4; NFKBIB; TFAP4; TBL1XR1; PSMD9; FOXN2; ZNF25; ZBTB43; BTAF1; SND1; RXRB; KLF4; TERF2; PHF5A; DOT1L; MDM4; MBD1; TDRD3; CALR; DNAJC2; BRF2; TAF12; TOPORS; MAFF; MITF; TCFL5; ATF6; MYC; RIPK3; TAF5; AATF; NR4A2; TFCP2; YBX3; HSF1; SIRT2; ZBTB24; AEBP2; PRDM2; THAP7; UBE3A; POLR3C; IKZF5; PPRC1; KDM5A; CIR1; GMNN; ATF5; TAF1D; MEF2D; CRY1; CEBPB; CCNC; ZNF317; BCOR; SIAH2; CLOCK; CEBPA; ZFP91; CREBZF; PIR; BLM; MED30; CREM; FOXK2; ZNF655; TFE3; CREBBP; USF2; ZBTB7B; ZBTB38; MEN1; NR1D2; ZNF592; URI1; SF1; MGA; TLE1; CEBPG; HIPK3; RORA; ATF7IP; PRDM4; ATF2
Down-regulation	119	ONECUT1; HES6; CITED2; LPIN2; PAWR; SP110; AJUBA; NFIA; RFX5; GTF2I; PDLIM1; NCOA7; KLF12; RBPMS; NFIB; CRYM; PCBD1; PML; RARB; FLNA; VGLL4; ZNF532; SMARCE1; CNOT6; ZNF467; ZBTB4; MYRF; TFCP2L1; NFKB1; RBBP8; HHEX; TRIP6; ARHGAP35; TEAD2; ONECUT2; ID4; ZNF266; CBX2; SMARCA2; NR2F2; TSC22D3; CREB5; ZFHX4; ZNF697; ZHX2; TCF7L1; TRIM32; ETS1; ESRRG; SOX6; ZNF22; ANKRD1; NR1H4; HIPK2; CUX1; C11orf95; THRA; TEAD3; JUP; MAGED1; TLE2; TULP3; PMF1; ZBTB45; DEK; HMG20B; NFE2L2; ZNF512B; IRF7; SSBP2; ZBTB8A; TEAD4; CEBPD; LMCD1; BHLHE41; NPAS2; PATZ1; ZNF517; ZBTB20; RBL1; VEZF1; PCGF2; SMAD7; ZFP90; HDAC11; NR1H3; ZMIZ1; ZNF618; STAT1; MEIS1; RXRG; TCF7L2; CBX6; MYCBP; WWC1; RELB; SKIL; HDAC1; NCOA4; CHD6; ZNF358; RFX3; DBP; SUB1; HELZ2; PSPC1; ZKSCAN1; ID3; LOXL2; TCF4; MAFB; MAPK8IP1; MAF; GLIS2; GATA6; PBX2; IRF9; NR2F6; ERF