Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00519	Chir99021	GSE130381	ESCs	Human	8h	10uM	EID1014

Response Information :

Types	Number	Response transcription factors
Up-regulation	167	SP5; ZBTB38; GBX2; DDIT3; SOX14; ZEB2; FOXB1; JDP2; ZNF286B; ZNF497; EGR3; NPAS4; TCF7; MLLT6; PRDM4; NRIP1; PROX1; SP9; ZBTB21; ZNF324; ZNF441; LEF1; MIXL1; SP7; CDX2; CREB5; EGR2; PGR; SALL3; ATF3; ALX3; MSX2; CAMTA2; BACH2; FOS; FOXA2; SMARCA2; TGFB1I1; JUN; EVX1; KLF7; KLF11; HNF1A; NEUROG2; ZNF460; CDX1; SP8; EGR1; PRRX1; CIITA; ZNF584; ZNF800; RARB; EYA1; KLF5; HR; ZIC3; PAX3; VGLL4; ZNF777; PRDM1; VGLL2; NR4A1; SETD7; KMT5A; TWIST1; MAEL; SALL1; ZFPM2; TBX3; IL16; KLF10; SOX6; RUNX2; ZNF614; HOXA1; RUNX1; YAF2; VAX2; DLX1; MECOM; SP6; HOXD1; IRF8; HOXA13; TBX15; PLAGL2; TP63; EGR4; ZNF229; NR0B1; ATOH8; SNIP1; DACH1; OSR2; MEIS2; BARX2; IFI16; HOXA2; HES4; SATB2; HOXB1; TXNIP; HAND1; PITX1; ZIC1; ZFP64; NEUROG3; MSX1; RFX4; ZNF683; SMYD1; CITED1; OSR1; HOXA3; TFAP2E; HOXD8; PLAGL1; SOX18; MEIS1; HOXA7; GSC; GATA4; HOXA5; SOHLH2; HOXB7; MED17; FOXC1; DMRT2; HOXD3; ZIC4; PAX2; ZNF831; HOXB4; HOXB2; EOMES; MNX1; EBF4; WNT3A; HOXB5; HOXC4; HOXB9; HOXB8; MSGN1; HOXA4; HOXC5; ZBED2; HOXD4; HOXC6; TFAP2B; TBX6; TSHZ1; HOXB6; FOXF1; HOXB3; HOXA6; FOXG1; GATA2; ZBTB16; DMRT1; ZEB1; SNAI1; ZNF705D; CDX4; HES7; RUNX3; GATA6
Down-regulation	160	TSHZ3; TP73; MTA3; NR3C1; BHLHE23; TGIF1; HES1; ZBTB44; VSX2; KDM5B; ZNF775; POU3F4; OLIG1; LHX8; ESRRB; MYCN; POU3F1; ZFP14; ARRB1; HBP1; FOXO1; MYB; HMX3; HHEX; TCF15; TFEB; SKIL; KDM4C; HMX2; ETS1; ERG; IKZF1; ZBTB12; MLXIPL; BNC2; TOX2; HESX1; ZBTB3; TRIM24; SOX10; ETV6; FOXO4; IRF2; ZNF34; OLIG2; SNAI3; HSFX2; HNF1B; PRDM14; ONECUT1; SIM1; HDAC9; ZNF483; NR3C2; PBX1; NPM2; TERF1; NR1I2; FOXO6; ZNF860; PBX3; CBX7; ANKRD1; ZIC5; JARID2; TCF24; RAX; DBX2; FEZF1; FOXD3; TRERF1; ZNF878; TCF7L1; SALL2; TLE2; KLF9; LHX5; IRF6; TOX3; SIX6; ZIC2; CTCFL; EYA2; ZNF157; HLX; TOX; ERBB2; FOXI2; DLX6; NPAS1; MYC; OVOL2; DNMT3B; CBFA2T3; MEOX2; FOXJ1; SCRT2; YBX2; UTF1; JMY; RXRB; SOX21; MAFB; TAF4; MESP2; NFE2L3; DTX1; ZSCAN4; LHX1; CRYM; NELFB; ETV1; NR4A2; AES; ZNF143; ACTL6B; PPARGC1A; FOXP4; OTX2; TFCP2L1; TFAP2C; SOX2; LMCD1; POU5F1; GRHL2; PRDM13; GRHL1; ZFHX2; FEZF2; BHLHE41; ZNF469; TCF7L2; LHX6; ZNF398; MYT1; NR2F1; NANOG; SPIB; HES3; BCL11A; TRIM22; ZNF165; MXI1; THRB; ESR1; RORB; NR1I3; OVOL1; MYF6; SOX1; AHR; TLE1; EMX1; ZSCAN10; CEBPA; OLIG3; LZTS1; ZNF512B; POU2F3; ZNF488