Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00517	Chir99021	GSE130381	ESCs	Human	48h	10uM	EID1012

Response Information :

Types	Number	Response transcription factors
Up-regulation	243	EVX1; HOXB4; HOXA1; VGLL2; HOXD8; HOXB5; CDX2; HOXB2; HOXC4; HES7; PKNOX2; HOXB9; HOXA2; CDX1; DDIT3; LEF1; VGLL4; HOXA3; NEUROG2; HOXB8; MSGN1; NR0B1; HOXB3; ELF1; HOXA5; MSX1; ID3; SNAI1; HMGA2; TSC22D1; SALL1; DACH1; SATB2; BARX1; ZIC1; SP5; HOXA7; HOXA4; MEIS2; HOXB1; HOXC5; ID1; PLAGL2; ALX3; HOXD3; GBX2; JUN; TXNIP; ZEB2; HOXB6; SOX14; ZNF614; MIXL1; MLXIP; ZNF286B; CDX4; ZNF578; CIITA; HOXD1; SMAD9; ZBED2; SALL3; HOXD4; OSR1; EBF4; TBX6; AFF3; JDP2; ZNF831; TEF; ZBTB20; SP8; ZEB1; ZNF497; PAX2; KLF10; YAF2; SCMH1; FOXB1; WNT3A; THAP6; HR; ZFHX3; CITED1; GATA4; ZNF711; ASXL1; KMT5A; MAF; ELK3; NRIP1; PRRX1; ZNF436; EGR3; SMAD6; PROX1; UBE2B; EGR1; ZBTB38; HOXA6; SERTAD2; OSR2; GSC; HOXC6; TBX3; EGR4; JAK2; HAND1; ATOH8; TAF1A; TCF4; RUNX2; ZBTB41; POU6F2; MSX2; ZBTB21; SP7; SIAH2; HNF1A; HSBP1; FOXC1; SETD7; AEBP1; RORA; MAML3; SP6; GTF3A; PLAGL1; TSHZ1; HOXB7; ZNF324; ZNF600; PPARG; ARID5B; PSMC3IP; ZIC4; SNIP1; RUNX3; ZNF516; HES6; FOXF1; ATF3; HOXC8; HOXA10; HES4; TCF7; HAND2; GATA6; NR4A1; IFI16; HOXA13; NPAS4; FOS; FOXA2; DMRT2; PAX3; HOXC9; CHD3; BMI1; ARNT2; VAX2; EGR2; ZNF250; KLF7; ZNF446; ZNF540; GATA2; HMX1; PGR; SHOX2; ZNF683; JUND; NEUROD1; MAK; MITF; MEIS1; CASZ1; PRDM4; ZBTB16; ZNF800; ZNF584; MESP1; SP9; SOHLH2; ZNF343; EN1; IRF8; RXRG; PRDM1; TBX15; KLF5; CAMTA2; ZNF236; MNX1; ZNF441; ELF4; BARX2; ZFPM2; MYOG; RFX4; KCNIP3; TFAP2E; TGFB1I1; CREB5; MED17; ZFPM1; ZNF248; PITX1; TBX10; BACH2; ZSCAN1; RARB; DLX1; RORC; IRF5; FOXD4L4; KAT2B; ARID3C; TWIST1; HSFX1; FOXD1; SOX18; TFDP3; IL16; FOXG1; LMO1; LYL1; ZNF528; FOXL1; HSF4; SOX6; TP63; FOXD2; RUNX1; HIVEP2; MAEL; ZNF781; KLF17; KDM5D; KLF14; HOXD13; SMYD1; ZNF560
Down-regulation	247	OLIG3; DNMT3B; ERG; SOX10; ZNF878; POU5F1; NR1I2; ETS1; TERF1; NFE2L3; POU3F1; MYB; MTA3; RORB; MLXIPL; JMY; PBX1; POU3F4; RING1; ZSCAN10; ZNF483; HBP1; MYC; ETV6; STAT3; ZIC5; ZNF165; NANOG; CCAR1; ETV4; ERBB2; HMX2; PRDM14; ZFP42; MEF2D; ZNF398; ONECUT1; JARID2; NLK; TSHZ3; SOX21; ZNF775; FOXP4; NR1H2; CEBPZ; HESX1; VSX2; ZNF469; FOXD3; SALL2; ZFP3; AES; ZIC2; ZMYND8; PIR; TRIM24; PSIP1; ZNF512B; TCF7L2; TLE2; TGIF1; HLTF; SOX2; WWC1; KLF9; SFPQ; FOXO1; NR3C1; GLI2; MAFB; CBX7; HSFX2; SIX6; IRF2; HDAC9; CITED4; ZNF770; OTX2; FEZF1; ZBTB3; ZNF860; ETV1; ZNF219; HMX3; ZBTB44; KDM4A; TFE3; CRYM; TCF7L1; SATB1; ZNF812P; PAWR; MYCL; TP73; HES1; OVOL2; GRHL2; ZBTB12; YBX2; TLE1; PPARGC1B; LHX4; PBX3; TOX; PSPC1; HES5; KDM4C; BCL11A; SOX1; TAF4B; ZNF311; MYCN; TOX3; EMX1; IKZF1; LHX1; OVOL1; ZNF233; ZNF34; ZBTB24; GRHL1; ZFHX2; DBP; NPAS1; RBPMS; ZFP57; SKIL; GLI1; ZNF488; ELF3; E2F8; TFAP2C; LZTS1; CREB3L4; OLIG1; DTX1; ESRRB; RXRB; ZNF69; ACTL6B; BRD3; FOXN3; PPARGC1A; UTF1; ZNF217; DACH2; IRF6; ADRB2; FOXJ1; BHLHE23; FOXI2; SNAI3; HES3; TRERF1; FOXO4; HHEX; ARRB1; ZNF239; LMCD1; AHRR; TFCP2L1; CBX6; MESP2; ZNF480; PAX8; SCX; BNC2; BCOR; ZNF157; BATF2; HTATIP2; CTCFL; LHX8; SIX2; SOX15; AHR; HEY1; POU2F3; ZNF101; ZBTB7B; ISL1; BCL9L; TRIM25; NR3C2; TEAD4; SSX4B; LHX6; TCF24; SPIB; ZNF425; CBFA2T3; TAF4; IRF4; LHX5; HNF1B; TFEB; CEBPA; TRIM22; SCRT2; THRB; MYF6; FEZF2; BHLHE41; NOTO; OTX1; DBX2; INSM2; NHLH1; SIM1; ERBB4; ATOH7; MKX; OLIG2; MEOX2; IRX5; RAX; HLX; PRDM13; NPM2; ZNF845; IRX4; KLF4; MYRFL; FOXO6; ARNTL; NR4A2; SP140; NR1I3; NR2F1; ZFP92; MYOCD; ANKRD1; BHLHA15; DYRK1B; CERS3; NFATC2; POU4F1; ZBTB7C; GRHL3; TULP1; MYT1L; EYA2; DLX6; ZNF648; PRDM9; NELFB; ESR1