Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00516	Chir99021	GSE130381	ESCs	Human	24h	10uM	EID1011

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	EVX1; NEUROG3; HOXA1; EOMES; CDX1; ZNF578; LEF1; CDX2; SOX14; IRX1; DACH1; PITX2; VGLL4; GBX2; SP5; FOXB1; MIXL1; SALL3; ZNF780B; ZEB2; IRX2; TEF; SP8; ZFP64; EGR3; ZNF812P; DDIT3; FOXB2; MLLT6; ZIC1; ZBTB38; REST; HOXB1; INSM1; MEIS2; PRRX1; FOXA2; SMARCA2; NRIP1; PLAGL1; ZNF311; GATA4; IRX6; ZNF836; FOXQ1; HOXA2; LHX4; JDP2; SCRT1; BARX1; MSX1; ZIC3; PROX1; KLF5; MSX2; VGLL2; LBX2; TBX3; GSC; YAF2; ID2; SP6; SKOR2; NEUROD1; IRF8; TCF7; HOXB2; IFI16; ATF3; HOXD1; ZIM3; OSR1; ZFP2; SP9; HNF1A; NR0B1; CARF; ZNF441; SETD7; DUX4; ZNF600; ZNF382; ZNF611; NACA2; SKOR1; PPARG; CAMTA2; RARB; MESP1; HSF4; HOXB3; ERBB4; ATOH8; PAX3; NPAS2; RFX6; PRDM7; HOXA3; ONECUT3; ZNF736; FOXD1; TBX15; POU6F2; MSGN1; HSFX1; ATOH1; ZIC4; MECOM; MYF6; HOXD3; PRDM1; HR; SP140L; RXRG; HELT; RUNX1; CREB5; DMRT1; FOXA1; OTP; SP7; GTF2A1L; HAND2; EGR4; WNT3A; CREB3L3; TWIST1; MEIS1; TBX4; SOX6
Down-regulation	128	TERF1; TAF4B; ERBB2; MYCN; POU3F1; PRDM14; TSHZ3; OTX2; NR3C1; MXD4; HES1; VSX2; DNMT3B; ZNF398; CCAR1; MYC; ETV6; ZFP42; SOX4; SALL2; FOXO1; JARID2; TRIM24; JMY; TCF7L2; SIX6; ZSCAN2; TFE3; GRHL2; POU3F4; HMX3; ONECUT1; ZBTB3; OVOL2; CRYM; RARG; FOXJ1; TP73; ID4; ZBED6; ACTL6B; HES5; SNAI3; HBP1; EMX1; TRERF1; ZNF439; KLF9; TCF7L1; FOXD3; ZFAT; ZNF143; SOX21; UTF1; AIRE; CDX4; BHLHE23; ZBTB12; RFX8; HLX; ESRRB; PAX9; ETS1; ARID5B; FEZF1; ZNF688; SIX2; HESX1; ZNF341; SMAD9; DLX6; GLI1; LHX8; BNC2; RORB; SPIB; EBF2; EYA2; SIM1; HEY1; ANKRD1; MAFB; NR4A3; SHOX2; NPM2; HIVEP3; CEBPD; MXD3; TXNIP; DBX2; AHRR; FOXI2; HMX2; DYRK1B; SOX1; PITX3; SIX1; MEOX2; BNC1; SP140; TLE2; TBR1; IKZF1; PEG3; MYOCD; FOXP4; ZFP57; TFEB; OLIG1; FOXO4; DMBX1; LHX5; RAX; KLF2; ZBTB7C; SOX7; ZNF467; ST18; TFCP2L1; OLIG2; GLIS1; NR2F1; NELFB; TLX2; ZNF98; EBF3; YY2; SOX10