Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00515	Chir99021	GSE130381	ESCs	Human	16h	10uM	EID1010

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	CDX2; EOMES; DDIT3; TEAD1; SOX14; CDX1; LEF1; HOXA1; SMARCA2; SP5; GBX2; ZNF362; HOXB2; MLLT6; VGLL4; ZNF460; FOXB1; HOXA3; ZEB2; ATF5; EVX1; MIXL1; ZFP64; IRX2; LHX4; ZNF812P; YAF2; DACH1; PSMD9; MEIS2; ZIC1; REST; HIPK2; CUX2; FOXA2; ONECUT3; JDP2; HOXB1; KLF11; ZIC3; SP8; PLAGL1; SALL3; MKX; SMAD3; NEUROG3; FOXB2; IRX6; ZNF70; PITX2; PLAGL2; INSM1; SKOR1; PROX1; VGLL2; RARB; ZNF142; PRRX1; SRCAP; ZNF778; NRIP1; ERBB4; WWTR1; EGR3; TBX3; ZMIZ1; REL; KLF5; KMT2D; ZBTB38; CASZ1; DUX4; NEUROG2; TCF7; PCBD2; HES3; ZNF660; SP9; ZFHX3; ISL1; IKZF4; ZNF311; ARID1A; GSC; HOXA2; EN2; SP6; MSX1; ZNF611; ZNF396; ZNF683; EBF3; MEF2B; ATF3; ZNF229; SETD7; SP7; EGR4; GATA4; DBX1; BARHL2; HAND1; ATOH8; NPAS2; IRX1; FOXP3; MESP1; NFE2; YY2; ZNF441; IRF8; POLR2A; HNF1A; ATN1; HSFX1; MYF5; TFAP2A; POU2AF1; PGR; ISL2; FOXP2; IL16; SKOR2; PAX3; LHX9; KLF4; ATOH1; ESR2; PAX5; THRB; MNX1; ZFHX4; KDM5D; TP63; DMRT1; ZIM2; MED17; MAEL; NEUROD2; RUNX1; MSX2; ZSCAN1; ZIC4; MEIS1; SOX6; FOXD1; ST18; CIITA; FOXF2; POU4F1; CREB5; HAND2; ARX; TWIST1; TBX18
Down-regulation	131	HNF1B; SALL2; TAF4B; KLF9; MYCN; FOXJ1; NFE2L3; FOXD3; ETV5; OTX2; TERF1; ERG; SOX4; VSX2; JARID2; ZBTB3; MEIS3; HES7; PRDM14; DNMT3B; MXI1; FOXO1; MDFI; HESX1; SOX10; CDX4; POU3F1; HMX2; SPIB; HMX3; TGIF1; SNAI3; ONECUT1; MAFF; TP73; RIPK3; TRERF1; HBP1; BHLHE41; RARG; MXD4; POU3F4; TEF; NR3C1; ETV6; HES1; AJUBA; TLE2; TSHZ3; UTF1; SMAD9; RORB; FOSL1; CBFA2T3; CRYM; ZNF143; IRF6; BARX1; MYC; RHOXF1; SIX2; ARRB1; BHLHE40; FOXO4; ID4; LHX8; EMX1; MAFB; FOXI2; EYA2; TFEB; ACTL6B; SIM1; ARID5B; TOX2; HES5; OLIG2; LMO1; TCF15; MEF2C; TRIM22; ANKRD1; WNT4; ASCL2; SOX21; SIX6; FLI1; CBX7; LHX5; SIX1; POU2F3; IRF4; MYOCD; ESRRB; DMRTA2; OVOL1; HLF; OLIG1; LHX6; GLIS3; GATA2; ZFP57; RUNX3; FOXS1; INSM2; RAX; MEOX2; GLIS1; BNC1; KLF2; FOXO6; BHLHE23; SCRT2; OLIG3; PITX3; POU3F3; SHOX2; HIVEP3; NR4A3; ASCL5; NELFB; NR4A2; TBR1; HIC1; LYL1; HSFX2; GATA5; PRDM16; ESR1; IKZF1; ZBTB16