Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00513	Chir99021	GSE130381	ESCs	Human	24h	10uM	EID1008

Response Information :

Types	Number	Response transcription factors
Up-regulation	187	TERF1; MYCN; DNMT3B; SALL2; FOXO1; ERBB2; MYC; HES1; PRDM14; POU3F1; SOX4; ZFP42; JARID2; TRIM24; TFE3; ZNF398; CCAR1; FOXD3; CTNNB1; CTBP2; ETV6; MXD4; ZBTB3; TGIF1; TSHZ3; FUBP1; GRHL2; SFPQ; CEBPZ; OTX2; TAF4B; ZBED6; NR3C1; ZNF143; HBP1; HMGB1; NLK; PSIP1; ZIC5; ZNF483; TGIF2; TRERF1; ZBTB44; SREBF2; TCF7L2; CRYM; RARG; NFE2L3; PBX1; HMGN3; RBM14; KDM5B; JMY; ZSCAN2; MTA3; TP73; CDYL; TCERG1; JUP; SAFB; ID3; AES; TCF7L1; PNRC2; KDM4A; TAF5; POU3F4; TUB; WDR77; USF1; FOXN2; BRD3; TFDP2; CREB3L2; FOXJ1; SAP30; HES6; FEZF1; ZBTB12; ZFAT; ETS1; ID4; BNC2; MED14; SPIB; SOX21; KLF9; SNAI3; EZH2; NOCT; CDX4; IRF2; TOX; ONECUT1; SAFB2; ZIC2; IRF6; ZNF439; RORB; RING1; GLI1; HDAC9; ZNF341; HMX2; ZNF878; GRIP1; TXNIP; TCF19; ZNF775; AJUBA; GPS2; ZNF101; LMCD1; ID1; ZNF624; UTF1; ZNF165; ZNF69; OVOL2; RXRB; RELB; KCTD1; ZNF628; GLI3; EMX1; DYRK1B; HESX1; ZNF488; ZNF684; TLE2; LZTS1; MXD3; CEBPD; ELF3; HEY1; ZNF688; PEG3; ZNF34; NPM2; AHRR; MAFB; ACTL6B; SMAD9; ZNF764; HIVEP3; TFEB; ZNF41; CBX7; MYB; ZNF785; PAX9; FOXP4; IKZF1; JAZF1; FOXO4; TCF24; OVOL1; ZNF157; ARID5B; DTX1; ANKRD1; ZNF324B; EYA2; TCF15; TFCP2L1; ZNF75D; IRF1; E2F8; ARNTL; FOXO6; MAML2; ZNF860; TOX2; MXD1; NPAS1; HCFC2; OLIG3; HNF1B; ADRB2; SOX15; ERG; SOX7; NR1I3; IRF4; FEZF2; OTX1; POU2F3
Down-regulation	215	MIXL1; EOMES; FOXB1; LEF1; SP5; GBX2; ZEB2; SALL3; VGLL4; CDX2; EVX1; SP8; HOXA1; REST; CDX1; NRIP1; SMARCA2; PRRX1; TBL1XR1; ZBTB38; DACH1; IRX2; MLLT6; FOXH1; TEAD1; ATF4; SOX14; ZIC1; DDIT3; ZIC3; ZFP64; IRX1; ZNF460; PROX1; ZNF780B; SALL1; ZNF558; HIPK2; LHX4; ZNF516; TEF; ZNF264; ID2; ZNF426; TCF7; ATF3; HOXB1; JDP2; ZNF581; MSX1; ZNF836; LPIN2; KLF11; ZNF578; PSMD9; CHD9; TCF4; YAF2; ZKSCAN2; SETD7; ZNF28; ZNF660; EGR3; FOXA2; SMAD3; KLF5; ZNF780A; TSC22D3; ZNF100; GATA4; ZNF600; NEUROG3; TBX3; SCAI; KMT2E; MSX2; LCORL; ZSCAN12; THAP6; RORA; PCGF6; ZNF611; GSC; SIRT2; WWTR1; ZNF382; ZNF730; NR2C2; ZNF812P; RELA; ZNF808; PAX3; IFI16; ZNF695; PLAGL1; ZNF311; ZNF737; IRF8; ZNF473; ZNF441; HMBOX1; ZNF816; MEIS2; ZNF420; WTIP; ZNF717; ZNF626; PRDM4; STAT5A; ZNF468; SP6; CAMTA2; KMT5A; ERBB4; CARF; ZNF777; ZNF501; ZNF621; ZNF681; ZNF805; CASZ1; FOXD1; HES3; ZNF285; BARX1; KLF12; PURA; ZNF70; INSM1; REL; MYRF; AFF3; ZSCAN23; IKZF2; ZFHX3; ZNF502; ZFP2; NFIB; ZNF667; ZNF224; BMI1; ZNF701; ZNF665; ZNF530; ZSCAN31; ZNF446; PCGF1; NPAS2; POU6F2; ZNF736; HEYL; PRDM7; ZNF20; HSF4; ZNF846; ARRB1; GLI4; PCGF5; EYA1; HES4; HOMEZ; ZNF800; ATOH8; TGFB1I1; ZNF236; ZFP3; TBX15; ZNF880; MEF2B; ZNF229; ZNF343; FOSL1; SP140L; ZNF674; IKZF4; NR5A2; ZNF425; HSFX1; PRDM1; ZFPM1; ZNF547; MYF6; SATB2; TBX6; EBF4; SOHLH2; NFATC2; NFE2; CREB5; MECOM; ZNF396; ZNF132; FOSB; TSHZ2; ZNF829; MESP2; GTF2IRD2; CIITA; RUNX1; L3MBTL4; FOS; ZNF454; ZNF630; ZNF583; HES2; SMAD6; POU5F2; ZFHX4; GRHL3; EPAS1; DCC; PAX5; ZNF528; MSC; SOX6