Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00454	Perhexiline	E-MTAB-798	Hepatocyte	Human	8h	0.6uM	EID0951

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	CCNA2; ZNF652; ZIC1; AFF3; CREB3L3; TCF19; SOX6; ARHGAP35; SUPT6H; CBX5; CENPF; KAT2B; PPARA; TOB1; PLAGL1; AES; FOXM1; IRF6; PTTG1; HMGB2; TCFL5; SLC2A4RG; TP53; PHF19; NR1H4; ZBED3; SSBP2; EPAS1; REPIN1; SOX4; JUND; BBX; PSIP1; HMG20B; ITGB3BP; ERBB2; MYRF; ZBTB45; MXI1; NFIC; HLTF; TSHZ2; TEAD2; CLOCK; ETV1; MAZ; TAF5L; PDLIM1; ZNF814; SOX5; CUX2; GLMP; PEX14; ZNF618; ZNF846; THRB; CREBL2; SALL1; ARID1A; MED16; EGR1; TBL1X; RFX5; LPIN2; STAT6; HNF4A; NCOA1; EHMT2; TFE3; MYBL2; AJUBA; TSHZ1; ZFP90; PBX2; MEN1; ZNF75A; PBX1; MED25; JUP; ATF6; ELP1; TCF3; STAT4; IRF2; TMF1; MBD3; TFDP2; HLF; ZNF512B; RNF20; HSF1; LITAF; ZBTB20; CITED2; RRN3; TRIM25; TFDP1; MAGED1; NR3C2; CBX7; GATA4; HIPK1; HMGA1; CRYM; E2F8; PIR; SATB1; CBX4; SAP30; RBPMS; BRD3; HDAC6; PCBD2; TRIM16; ARRB1; MTDH; ETV5; PROX1; KDM4C; MYBL1; TCF7L2; INSR; ZNF12; HMBOX1; CTNNB1; PPARGC1A; NFIA; CALR; TRIM22; ZKSCAN1; SMAD2; CNOT3; NSD2; ZNF292; NPAS2; ZNF791; CBFA2T2; SMARCC2; HIPK2; ZNF678; ZSCAN2; BRCA2; CDIP1; SREBF2; BRCA1; ARNT
Down-regulation	112	LMCD1; ANKRD1; IFI16; BCL10; PPARD; THAP2; MAFF; TAF1D; KLF6; SFPQ; TXNIP; ENO1; ZNF131; MAFG; ELK3; NACA; ZNF654; ARL2BP; ZNF281; MAF; NR2C1; STAT3; MYCL; ETS1; SRF; ZNF267; TSC22D1; ZNF23; TSC22D3; ELF3; HNRNPD; PRRX1; MED21; MAFB; SOX7; ARNTL2; ZNF880; ZNF432; YY1; KLF7; TOX; ID2; MED10; ADRB2; ZBTB34; ZNF770; CDK7; MLXIP; TRIM33; PHF20; ZFY; FOXO1; EPC1; BHLHE40; ASH1L; NPM1; HEY1; ZNF302; UBE2L3; SKIL; BASP1; KLF4; PURA; ZNF286A; ZNF8; TBX3; RCOR3; PHF5A; THRAP3; ETS2; ARID3B; PSPC1; CRY1; ZEB1; PNRC2; CHD7; NFKBIZ; NFIB; JUN; RUNX1; ZBTB43; FOS; HES1; ATF3; ZNF468; KDM5C; FOSB; MED31; RBM39; HIVEP2; GTF2A2; ZNF3; NLK; ASXL1; SPEN; NKX3-1; PCGF5; NOC2L; MED30; BCOR; KLF2; PAWR; ZNF655; DDX17; ARID5B; MXD1; TAF1A; BRD4; UBE2I; ZNF33A; HTATIP2; BRD7