Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00432	Mexiletine	E-MTAB-798	Hepatocyte	Human	8h	60uM	EID0929

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	MYBL1; CCNA2; PTTG1; HMGB2; SOX7; LMCD1; THRB; ANKRD1; E2F7; CHD2; E2F8; ZNF573; ZFY; ZHX1; YBX3; MAFG; ITGB3BP; ENO1; ZNF302; SMARCA1; JUN; PHF20; NFIB; ID2; PSMC3IP; THAP6; TCF19; CENPF; EZH2; DR1; ZBTB26; TFDP2; FOXO1; ZFP36L1; NSD2; ZNF101; MITF; SUV39H2; ZNF420; LOXL2; ZNF544; ZNF605; PRMT2; TRIM16; ZEB1; ZNF567; ZBTB44; PHF19; FOSL2; SMAD1; RBBP4; MED31; TAF1A; ARL2BP; KDM5D; ZNF770; PKNOX1; ZNF283; HMGB3; YY1; FOXM1; ZBTB41; ZNF93; ZNF550; ZNF234; MYBL2; SFPQ; PLRG1; PURA; ASH1L; DDX54; CTBP2; SOX4; ZNF449; TRIM33; PSIP1; NUP62; CREB5; INSR; CBX5; ZNF131; NFYB; MIER1; ZNF281; ZNF226; ZNF569; CERS6; CREBZF; ZNF432; ZNF532; ZNF559; TBL1XR1; PAWR; ZNF595; PCGF5; NAB1; SAP30; BRCA2; CDK2; NCOA2; CBX3; FOXN3; ZNF655; TAF9B; RB1; ZNF654; ZNF514; ARID1B; GTF2I
Down-regulation	74	NR1D1; REPIN1; MKX; ZNF652; TRIM29; ZBTB20; EGR1; TFE3; HNF4A; IRF9; WIZ; ZBTB45; KLF4; IRF3; PAX8; JUND; KLF7; CBX4; FOXA3; PBX2; CAPN15; SOX6; NFKB2; BCL3; KLF9; EP300; KMT2D; THAP8; FOXQ1; ETV1; SSBP3; ZIC1; JUP; HDAC6; ELK1; HHEX; NR1D2; TAF6L; FOXK2; SUPT6H; ZNF618; BRD3; MAZ; SMARCD1; ZNF689; CEBPA; PROX1; NFIC; CREB3L3; TADA3; TP53; TBL1X; UBE2B; CUX1; GATAD2A; KDM1B; RXRA; CNOT3; KDM5C; TSHZ2; ARHGAP35; EPAS1; ATF5; SOX5; TOB1; KMT2C; AFF3; HIPK1; ARID1A; SOX9; ING3; NFIA; HIRA; ETS1