Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00427	Methyldopa	E-MTAB-798	Hepatocyte	Human	8h	50uM	EID0924

Response Information :

Types	Number	Response transcription factors
Up-regulation	47	LMCD1; KDM5D; PTTG1; ZFY; CCNA2; ANKRD1; ENO1; FOXM1; HMGB2; YBX3; MYBL1; ZFP36L1; TAF1D; FOXO1; THRB; CDK2; ATF3; MAFG; NFIB; MAFF; KLF6; NOC2L; SOX4; LOXL2; PSMC3IP; NOCT; ITGB3BP; MED31; HTATIP2; E2F8; ZNF3; INSR; ARL2BP; SFPQ; UBE2I; MDM2; KLF5; PHF20; CREB5; CENPF; TFDP2; EZH2; SOX7; DDX54; CHD2; PCGF5; PAWR
Down-regulation	136	EGR1; PROX1; ZNF652; HLF; SOX6; MAFB; TSHZ1; ZNF618; ETV1; ATF5; SALL1; MAML3; EPAS1; MTDH; HNF4A; SATB2; CBX4; HES1; TOB1; BBX; SOX5; ZKSCAN1; HHEX; MXI1; FOXQ1; ADNP2; KMT2C; NR1D2; RORA; ZBTB8A; SATB1; TBX15; ZNF57; MEIS2; FOXA3; ZFP90; ZBED3; CLOCK; ARHGAP35; MYRF; CEBPA; BCL3; CREB3L3; KLF9; TBL1X; HIPK2; JUP; ZNF148; WWP1; ZIC1; ZBTB38; ZNF292; ZNF678; RBPMS; ZNF30; TSHZ2; BRD3; SOX9; SUPT6H; TCFL5; ZBTB40; CITED2; BAZ2A; ATF6; RXRA; RSF1; CALR; BPTF; PPARGC1A; NFIA; RARA; MAF; ARID2; IRF9; RORC; ZBTB20; NR2F2; MLLT10; TRPS1; IRF7; TEF; NR5A2; USF3; NR1H4; ZSCAN29; LPIN2; ZNF107; NCOA2; ZNF131; TRRAP; MBD1; ZEB1; EHMT1; ZBTB45; PPARA; SSBP2; TRIP11; ID1; KDM1B; ZNF786; AFF3; RREB1; ZNF558; ZNF397; PBX2; ZNF12; ZNF512B; KLF13; CAPN15; KMT2D; NCOA3; NFIC; ARID1A; ZKSCAN7; HIPK1; CBFA2T2; CEBPD; TRIM29; FOXA1; IRF6; NR3C2; ARID1B; GCFC2; ATOH8; BCOR; ZXDC; CNOT3; SSBP3; GATA4; EP300; DDX17; ZNF561; SPEN; PURA; MAZ; IRF2