Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00426	Methimazole	E-MTAB-798	Hepatocyte	Human	8h	2000uM	EID0923

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	ANKRD1; ARL2BP; ENO1; LMCD1; BASP1; YBX3; ATF3; KLF6; TAF1D; MAFF; NFIB; PHF20; ID2; LOXL2; KLF7; MAFG; ELK3; BCL10; TRIM33; THAP2; PLAGL1; ZNF131; ZNF3; CHD2; TBX3; PAWR; TCF4; SOX7; IFI16; NUP62; ZNF654; ASH1L; CDK2; THRB; FOXO1; ARID5B; ZBTB44; TSC22D2; MLXIP; KLF5; GLIS3; PURA; ZFP36L2; HMGA2; TEAD4; JUN; SIN3A; NOCT; SETD3; ZNF281; YY1; MEF2C; ZNF655; ZNF302; TAF1A; ID3; GABPB1; FOSL1; EPC1; ZNF670; RUNX1; UBE2I; FOSL2; ZBTB34; WWC1; THAP6; ZNF532; PSMC3IP; PRRX1; ZNF23; HEY1; NOC2L; NACA; HTATIP2; PPARD; DDX54; SFPQ; CTBP2; PMS1; ZNF573; GTF2I; SOX4; USF1
Down-regulation	88	HLF; TRIM22; AFF3; SALL1; FOXA3; CITED2; ZNF652; BTG1; ATF5; IRF6; ZBED3; HNF4A; NR1I2; TBX15; BBX; ZNF618; EGR1; NFIA; ARHGAP35; IRF7; CREB3L3; MXI1; SOX6; REPIN1; CBX4; ZBTB20; LPIN2; EPAS1; HHEX; TSHZ1; SOX5; NR1H4; ZNF512B; NFIC; TOB1; PPARA; JUP; WWP1; MED16; PROX1; MAGED1; TBL1X; TP53; ETV1; ZIC1; FOXA1; SATB1; CEBPA; CBX5; ONECUT1; ZNF12; GATA4; ZNF467; CNOT3; HDAC6; TADA3; HIPK1; NFKB2; USF3; RORA; SSBP3; ERBB2; STAT6; MAZ; BRD3; SLC2A4RG; TCFL5; ZNF814; CDIP1; CRYM; ARID2; ESR1; JUND; CALR; PCGF3; NPAS1; TXNIP; ETS2; TBX1; MAFB; KDM1B; WIZ; MAF; RARA; ZBTB45; TFE3; ETV5; NR3C2