Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00410	Hydroxyzine	E-MTAB-798	Hepatocyte	Human	8h	8uM	EID0907

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	ANKRD1; LMCD1; IFI16; MAFF; KLF7; TOX; ID2; MAFG; MAF; ARID5B; THAP2; TXNIP; ATF3; ENO1; JUN; TAF1A; ETS1; DDIT3; TAF1D; ARL2BP; SRF; BCL10; ZNF302; EPC1; FOS; ZNF165; ZNF880; KLF6; CREM; SFPQ; PPARD; ZNF697; ID3; ZNF655; BASP1; CCDC59; ZNF222; ZNF561; STAT3; MED17; MKX; ZNF567; ZNF573; CREB5; MED21; ZNF654; ZNF131; PNRC2; TGIF1; ZNF23; YBX3; MEF2A; ZNF211; ELK3; NFKBIZ; ZNF670; NPM1; ZNF3; NACA; MED1; MXD1; ZFX; GZF1; NFIL3; MED6; BCLAF1; MAFB; USF1; PAXBP1; ADRB2; CTBP2; SETD3; NOC2L; SUPT7L; ARNTL2; MLXIP; MED4; ZBTB43; TBPL1; TBX3; ZNF8; CHD2; PSPC1; THRB; SMAD1; ASH1L; ZFY; ZEB1; FOSL2; ASXL1; ZNF805; ZNF143; BRF2; ZNF22; SKIL; NR2C1; MAX; ZNF267; RCOR3; ZNF555; PAWR; MIER1; PHF20; SAP18; HMGA2; GABPB1; ATF1; CREBZF; ZHX1; ZNF432; ZNF112; TRIM33; KLF2; DDX17; ZNF529; ZNF281; ZNF146; GTF2I; RBM39; ZNF286A; ZNF614; SOX7; PURB; PRRX1; MED30; HNF4G; FOXO1; MED31; BACH1; HNRNPD; ZNF37A; MYCL; ZNF770; SUMO1
Down-regulation	111	SOX6; ZBTB20; REPIN1; STAT6; TBL1X; ZBED3; ZNF652; ZNF618; MYRF; NR1H4; NFIA; RBM14; CUX2; PROX1; EPAS1; KAT2B; HIPK2; SUPT6H; CBX5; CCNA2; TOB1; TSHZ1; TCF19; SREBF2; PAX8; FOXQ1; JUP; PSIP1; LPIN2; HLF; PPARA; IRF6; PHF19; ARHGAP35; ERBB2; HDAC6; SMAD2; FOXM1; CITED4; NFIC; CITED2; ATOH8; SSBP2; PBX1; HNF4A; BRCA1; ETV1; MYBL1; ARID1A; IRF2; MXI1; HMG20B; SOX4; ARID1B; BBX; L3MBTL2; ELP1; SOX5; MEN1; PDLIM1; PIAS1; E2F8; JUND; ZBTB16; SOX13; ATF6; TRRAP; SALL1; MAZ; AES; TADA3; RXRA; TRIM25; TSHZ2; ZKSCAN1; TFE3; KMT2D; ZNF12; TLE1; GLMP; PEX14; ZBTB38; ATF5; SATB1; CHAF1B; ZNF787; TONSL; TP53; NCOA2; ZHX2; ZNF512B; CLOCK; NFIX; CREB3L3; CUX1; HIPK1; ARRB1; ZNF292; TEAD2; CERS4; HLTF; PLAGL1; PPARGC1A; RBPMS; KMT2C; WWP1; GATA4; AFF3; FOXN3; TRIM29; OSR1