Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00384	Cyclophosphamide	E-MTAB-798	Hepatocyte	Human	8h	80uM	EID0881

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	IFI16; ANKRD1; LMCD1; DDX17; THRB; ID1; TXNIP; ARNTL2; ENO1; YBX3; EID1; NFIB; CCNA2; KLF6; ZNF880; SUV39H2; HNRNPD; PHF20; NCOA7; ASH1L; TRIM22; ID2; TAF1D; ARL2BP; SMAD1; YAP1; NAB1; STAT1; CBX5; PSMC3IP; PMS1; MYBL1; ZNF22; CNOT2; SMARCA1; TFDP1; LOXL2; KLF7; E2F8; ZNF3; CDK2; ITGB3BP; HDAC8; ZNF655; CREB1; PRMT2; CREB5; MLXIP; NACA; SMARCAD1; PEG3; ZNF367; TBL1XR1; GTF2I; RB1; E2F5; CBX3; ZNF544; ETS2; INSR; SFPQ; HMGB2; ZNF720; NFIC; MDM2; SOX4; FOSL2; ZHX1; CCAR1; ZNF302; ZNF264; USF1; ZNF664; TOX3; PRRX1; BASP1; EZH2; CTBP2; TAF9B; MKX; ZNF268; SUPT7L; TAF1A; FUBP1; PCBD2; ONECUT2; ID3; USF3; SMARCA5; ZNF217; ZNF195; ZNF23; STAT2; ZBTB44; PAWR; TTF2; SRSF2; NOC2L; RCOR3
Down-regulation	214	HIPK1; ZNF292; ZBTB43; NR0B2; FOS; EGR1; FOXA3; ZBTB20; NR1D2; ZNF618; KDM2A; ZNF57; BAZ2A; POLR2A; UBE2B; TOB1; JUP; PLAGL1; CBX4; BRD2; CITED2; BRD4; TSHZ1; TFE3; ZNF791; KAT6B; BRF2; JMY; FOSL1; FOXO3; HBP1; ZBTB38; ZNF473; ZNF408; ZNF652; ZEB1; MED13; CALR; ZNF787; SMAD7; ZFP36L2; RORA; KAT7; KLF4; HMG20B; HIC2; FOXK2; RYBP; NRIP1; HMGA1; HEY1; FOXJ3; MXI1; KMT2C; KLF16; SUPT5H; KMT2D; MRTFA; BTG1; HIPK2; PRDM2; ZMIZ1; KDM5A; SPEN; ZNF746; NR1H2; KDM5C; SREBF2; GTF2IRD1; CREB3L3; CBFA2T2; LITAF; ARID1A; ARNT; CHD8; TRIB3; FOXJ2; SETD2; ADNP2; RNF4; ZNF436; MYRF; GMEB1; NCOA1; ABL1; ZBTB40; KMT2A; RBM14; SOX13; EP300; ZBTB21; BBX; MAFF; PIAS1; ARID3B; ZNF559; MED16; ZNF77; IRF6; ZNF165; CTR9; KLF11; MAFB; ZNF12; ATF3; SUPT6H; GLMP; ZMYND8; ZNF275; PHF1; ASXL1; CTBP1; SKI; HDAC5; MED26; PPARA; MBD1; YY1; TEAD1; KAT6A; HDAC6; AFF1; AIP; ZNF688; GATAD2A; SALL1; PROX1; TRIM28; TRIM11; LPIN2; MTDH; RLF; ZNF394; FOXA1; PPARGC1A; MAFK; ZBTB17; ZNF282; NR2C2; FOXQ1; NR1D1; AES; CBL; IRF9; ELK1; RBPMS; ZSCAN2; SNIP1; FOSB; TBX3; USF2; ZNF407; EPC1; PHF8; UBTF; ERBB2; MAFG; GZF1; KLF9; KLF2; BCOR; ZBTB24; CEBPA; SERTAD2; SAFB2; REPIN1; THAP8; CIZ1; ZFP37; ZNF513; TOPORS; TRAK1; BCL6; AFF4; NFIX; ZNF586; SRF; RELA; WIZ; ZNF281; GATAD2B; NSD1; MED12; PCGF3; NR4A1; JUND; TLE4; HSF1; PLAGL2; DOT1L; ARID4B; CAPN15; ZNF554; GRHL1; NCOR2; ETV3; MSX1; AGO2; ARHGAP35; TOX4; NR4A2; MEF2D; ATF5; SOX6; STAT6; NFAT5; TCF7L2; EHMT2; SKIL; SP2; MAZ; ZNF654; ZNF362; CNOT3