Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00382	Cyclophosphamide	E-MTAB-798	Hepatocyte	Human	8h	2000uM	EID0879

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	CCNA2; MYBL1; PTTG1; SOX4; NFIB; CENPF; ANKRD1; KDM5D; THRB; LMCD1; CDK2; INSR; CUX2; PSMC3IP; SMARCA1; HNRNPD; HMGB2; TCF19; E2F8; SMAD1; NAB1; YBX3; SUV39H2; EZH2; ARNTL2; PMS1; ZNF544; TFDP2; ITGB3BP; PHF19; PEG3; EID1; FOXO1; ZNF367; TFDP1; ZNF101; FOSL2; ZNF22; PSIP1; PURA; KLF6; ZNF720; TRIM16; CBX3; NFIC; TAF9B; ZNF3; ZNF573; TAF1A; FOXM1; CNOT2; ENO1; CREBZF; CBX5; DEK; PHF20; KLF7; ZNF302; YAP1; MITF; ASH1L; ZHX1; GMNN; WWTR1; KMT5A; SMARCA2; SNAI2; CHD2; HMGB3; RB1; MLXIP; L3MBTL4; TBL1XR1; SMARCAD1; CREB1; ZBTB44; ZNF664; USF1; MYBL2; SOX7; FOXN3; PCGF5; TTF2; TAF1D; ZBTB16; TGFB1I1; FUBP1; NUP62; PRMT2; ZNF512; ZNF655; NOCT; BRCA1; LOXL2; NSD2; ZFP36L1; ID2; CREB5; BASP1; DDX54; CHAF1B; WWC1; KLF5; ELF3; ARL2BP; DDX17; KLF12; CERS6; ZFY; THAP6
Down-regulation	163	FOS; EGR1; NR0B2; ZBTB43; HIC2; CBX4; BRD2; ZNF292; FOXJ3; AFF4; TFE3; TOB1; ZNF473; ZBTB38; KLF4; MAFB; UBE2B; ZNF57; CALR; JMY; KDM5C; RBM14; MEF2D; NR1D2; ZBTB20; MAFF; MTDH; EP300; KMT2C; SKI; BRF2; ZEB1; KLF2; KDM2A; MED13; HIPK1; ZNF618; CITED2; BCL6; TSHZ1; BRD4; SPEN; MBD1; NFRKB; ARID3B; BTG1; FOXK2; RYBP; ZNF408; PRDM2; ZBTB21; CREB3L3; MRTFA; TRIB3; ZNF148; ADNP2; ZNF652; KAT6B; ZFX; HBP1; BAZ2A; NRIP1; ZNF746; NR2C2; KLF16; MXI1; JUP; HEY1; ZNF791; FOXQ1; REPIN1; CTBP1; TRIM29; ZSCAN25; SOX9; AFF1; WIZ; HIPK2; SALL1; SNIP1; HHEX; FOSL1; EPC1; ZNF77; TOPORS; ATF3; FOXA3; ZNF513; HDAC5; USF2; DDIT3; ZBTB24; ZNF394; ARNT; ATF5; XBP1; FOXA1; ZNF12; KDM5A; POLR2A; RXRA; MAFK; GZF1; CSDC2; BBX; KMT2D; ABL1; TOX4; CTR9; KMT2A; ZMIZ1; ZIC1; PLAGL1; ING3; CREM; TBX3; CHD8; UBTF; ZBTB40; KLF9; ZNF436; GATAD2B; FOSB; ZNF557; SOX13; TRIM28; GATAD2A; GMEB1; IRF9; RLF; MED26; NR1D1; RXRB; ETV3; PROX1; FLNA; KAT5; CCDC59; MGA; AGO2; SRF; TBX15; ARID1A; CEBPA; ARHGAP35; RORA; MXD1; ZNF24; MED12; KDM5B; KMT2E; RELA; NR4A2; BCOR; SUPT6H; DOT1L; EPAS1; PLAGL2; ZNF654; HSF1; SSBP3; MAZ; SOX6