Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00321	Labetalol	E-MTAB-798	Hepatocyte	Human	2h	28uM	EID0818

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	SOX6; CCNA2; CENPF; CUX2; KAT2B; FOXM1; TCF19; LPIN2; ETV1; ZIC1; PROX1; PPARA; MYRF; PSIP1; HMGB2; TBL1X; NR1H4; TRIM22; AES; TRIM25; HMG20B; FOXN3; PTTG1; ZBTB20; ZSCAN2; SOX5; MXI1; E2F8; HIPK2; SOX4; ARID1A; PBX1; NFIC; ZBED3; ZKSCAN1; ERBB2; SALL1; PIAS1; NSD2; ZNF512B; TLE1; CREBL2; SMARCA1; HNF4A; SMARCA4; PDLIM1; TSHZ2; TSHZ1; ZBTB16; ZNF618; MDM2; HDAC6; MYBL1; STAT4; CREB3L2; EPAS1; IRF6; IRF9; HLF; MAGED1; CREB3L3; ZNF12; FLNA; SATB1; CBX5; GLMP; LIMD1; TFDP2; PPARGC1A; CRYM; HLTF; CITED2; REPIN1; TOB1; ARHGAP35; CERS6; SLC2A4RG; TRRAP; RFX5; PLAGL1; BBX; SMARCC2; TEAD2; ZFP90; SSBP2; RFC1; TFE3; ELP1; KLF12; BPTF; SREBF2; ZBTB38; CERS4; CEBPD; ZNF292; ZNF652; TAF5L; CAVIN1; AFF3; TP53; MED24; ZHX3; SMAD2; NPAS2; CARHSP1; SCMH1; CITED4; ATF5; STAT6; CNOT3; RORA; HMBOX1; NR1H3; ARRB1; MAZ; ZNF846; CHD6; TCFL5; ATF6; CBX7; BRCA2; MYBL2; CDIP1; PRKDC; ATOH8; MED14; CLOCK; GATA4; PAX8; CIZ1; NR3C2; BRCA1; MECP2
Down-regulation	132	LMCD1; ANKRD1; IFI16; PPARD; MAFF; KLF7; BCL10; THAP2; ID2; ETS1; TOX; EPC1; TAF1D; SRF; ATF3; MAF; ADRB2; JUN; MAFG; FOSL1; ZNF281; NACA; ZNF880; ZNF131; NKX3-1; PHF20; MLXIP; STAT3; MAFB; KLF6; MED21; ZNF23; NOC2L; DNAJC2; ELK3; ZFX; HEY1; PAWR; ENO1; ARL2BP; CAMTA2; FOS; ATF1; PURA; TSC22D1; GABPB1; KLF2; ZFP69B; PAXBP1; CDK7; ZNF354A; ID3; SAP18; SFPQ; CREM; SOX7; MAX; ARID3B; PURB; ZFY; ZNF267; PHF5A; PRRX1; FOSB; NUP62; BRF2; ARNTL2; MED17; ZNF146; ARID5B; DDX54; MED10; GTF2A2; MYCL; MED30; HES1; SNIP1; CCDC59; SKIL; NPM1; YAP1; ASXL1; POLR3C; TEAD4; ZNF670; ZNF697; THRAP3; MED13; RCOR3; NFYA; TBX3; NFIL3; HNRNPD; BAZ1A; ZNF770; NOCT; ZBTB2; ASH1L; ZNF22; BRD7; MKX; SIRT7; ZNF33A; ZNF174; ZNF800; ZNF8; PNRC2; GZF1; PRDM2; RLIM; PMS1; ZNF654; NR2C1; KLF5; FOXO1; RBM39; ZNF850; KLF4; HLX; NLK; ZFP36L1; USF1; TAF1A; MXD1; MED4; ZEB1; YY1; PCGF5; ZNF567; ING3; SUMO1; RNF6