Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00278	Terbinafine	E-MTAB-798	Hepatocyte	Human	24h	15uM	EID0775

Response Information :

Types	Number	Response transcription factors
Up-regulation	145	LMCD1; MAFG; IFI16; MAFF; THAP2; SRF; TXNIP; ID2; KLF6; ARL2BP; ATF3; PPARD; TAF1D; ANKRD1; ARID5B; ETS1; ENO1; MAFB; MED10; FOS; MAF; ZFX; ZBTB34; PCGF5; ELK3; KLF7; USF1; TSC22D1; CREM; ATF1; NOC2L; ZNF33B; JUN; DDX17; EPC1; ASH1L; PRDM2; ARNTL2; CDK7; PSPC1; TRIM33; ZNF697; MED6; ADRB2; ZNF131; ZNF33A; UBE2L3; MED17; ATF4; NFYA; ZNF22; MED31; CCDC59; DNAJC2; ZNF880; BRD2; PNRC2; HLX; MLXIP; ZNF146; ZBTB24; ZNF654; KLF11; KLF4; PHF20; ZBTB43; PHF5A; NPM1; ZNF23; E2F6; SFPQ; BCL10; TAF1A; ZNF354A; MED30; NACA; ARID3B; CREB5; MXD1; PRDM10; HSBP1; ZNF639; THRAP3; PKNOX1; PURB; AATF; PRRX1; FHL2; BRF2; ZFY; CHD7; TSC22D3; ELOB; GABPB1; MAX; FOSL1; ZNF267; SUPT3H; BANP; NUP62; ZNF263; BASP1; FOXJ1; POLR3C; ZNF557; SNW1; SAP18; GTF2A2; ELF1; TRIM27; MED1; TRIB3; YAP1; MTF1; ID3; ADNP; FOXO1; MED21; TOX; PCBD2; TBPL1; RUNX1; ZNF24; KMT5A; ZNF670; ZNF529; ZEB1; ZNF211; ZNF823; SKIL; CAMTA2; RBM14; KLF2; ZNF3; SIRT7; GMEB1; STAT3; ZNF432; HNRNPD; HES1; HNF4G; ZNF614; SOX7; MIER1; ZFP69B
Down-regulation	206	SOX6; CCNA2; TBL1X; ZNF652; KAT2B; IRF6; BBX; ZIC1; SALL1; PROX1; SATB1; CUX2; AFF3; LPIN2; CITED2; ERBB2; SUPT6H; FOXM1; ETV1; TOB1; AJUBA; STAT6; NFIC; MYRF; PPARA; HMGB2; TSHZ1; PBX1; HIPK2; AES; FOXN3; ZFP90; SMARCA2; HDAC6; SSBP2; EPAS1; CLOCK; MXI1; IRF2; NR1H4; JUP; PDLIM1; ZKSCAN1; SOX4; SREBF2; ZNF618; ZNF512B; REPIN1; MAGED1; ZBED3; ZNF561; TRIM22; HLF; TAF5L; TP53; ATF6; SOX5; PAWR; CREBL2; SMARCA1; ATOH8; CDIP1; CENPF; ZBTB38; CREB3L2; ZBTB20; GATA4; TFE3; CREB3L3; HNF4A; INSR; PSIP1; NCOA2; CITED4; ARHGAP35; RXRA; ZBTB45; NPAS2; ZHX2; TRIM25; ZNF292; USF3; KDM4C; TCFL5; ZNF514; KLF15; TRRAP; PPARGC1A; ZSCAN2; ZNF12; TCF7L2; MYBL1; FLNA; ARID4A; MTDH; SAP30; NCOA1; TMF1; CHD6; TCF3; ZNF75A; TRIP11; SMARCC2; ZNF362; E2F8; MEN1; WWC1; BRD3; ELP1; LITAF; CBX5; PRKDC; TSHZ2; MED16; HLTF; HDAC11; TFDP2; EHMT2; ZBTB16; RNF20; NR1H3; RFX5; ZNF846; TLE1; HMG20B; PBX2; NFIB; JUND; CRYM; RORA; PCGF3; ZNF688; PHF19; MRTFB; MTA1; TFDP1; ZBED1; MTA3; CNOT3; ZFHX3; TBL1XR1; ZBTB8A; ETV5; PML; PTTG1; ARID1A; PARP1; PURA; VEZF1; HIPK1; WWP1; CERS4; BAZ2B; ZNF791; SLC2A4RG; ATF5; RERE; RSF1; ARNT; RFC1; NR5A2; TCF19; NSD2; NR3C2; BCL3; AFF4; NFIA; ZNF467; WIZ; CEBPD; ZNF814; CAVIN1; ZNF678; RBPMS; TEAD2; BRCA1; MYBL2; ARNTL; CBX4; ZXDB; MED24; EHMT1; E2F7; MED14; SMAD3; HHEX; FOXA1; ITGB3BP; MAZ; GLMP; PLAGL1; ZHX1; SSBP3; HMGB3; STAT4; ARRB1; BAZ2A; FOXP4; THRB; PIAS1; HMBOX1; CALR; KLF12; TBX1; ZSCAN18; PHF12