Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00265	Promethazine	E-MTAB-798	Hepatocyte	Human	24h	7uM	EID0762

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	SOX6; CCNA2; CREB3L3; IRF6; ZNF652; NR1H4; KAT2B; ETV1; PROX1; ARHGAP35; ZNF512B; HMGB2; E2F8; GLMP; ERBB2; PSIP1; CUX2; PTTG1; CBX5; SATB1; ZBTB20; TRIM22; HDAC6; TBL1X; MDM2; HLF; CREBL2; PBX1; MAGED1; REPIN1; EPAS1; TSHZ1; MYRF; AES; TOB1; RSF1; NPAS2; FOXM1; PDLIM1; CITED2; MXI1; IRF2; AFF3; ZNF12; HNF4A; SOX5; SMARCA1; HMG20B; SMARCC2; LPIN2; ZIC1; CALR; TCFL5; SREBF2; PHF19; SSBP2; TP53; NFIC; RNF141; ZBED3; NSD2; SUPT6H; ELP1; HLTF; STAT4; PLAGL1; THRB; ZKSCAN1; TRIM25; ZNF618; PAWR; ZNF846; ITGB3BP; CREB3L2; SALL1; BRCA1; CITED4; MTDH; ZNF467; ARID1A; NFIA; BBX; L3MBTL2; MYBL1; ZFP90; TMF1; MRTFB; ATF6; SLC2A4RG; PPARGC1A; ARRB1; PIAS1; SMAD2; ZHX3; NR3C2; HIPK2; SMARCA2; TCF19; SOX4; RFX5; CLOCK; CARHSP1; CDIP1; BAZ2B; PPARA; NR1H3; CENPF; WWP1; ZNF75A; ZBTB38; AJUBA; TSHZ2; RRN3; CBX7; IRF9; ZSCAN2; ARNT; TLE1; USF3; RNF20; NAB1; NR5A2; ZNF148; LIMD1; ZNF814; MAZ; CHD6; HDAC4; CRYM; TFE3; RORA; STAT6; HDAC11; CERS4; FOXN3; AFF4; CEBPD; TCF7L2; BPTF; MED24; JUP; MED16; HCFC2; PRKDC; FOXO3; TRIP11; MED14; GATA4; ARID4A; FLNA; TRRAP; ZNF337; CNOT3
Down-regulation	153	LMCD1; ANKRD1; MAFF; THAP2; PPARD; KLF7; SRF; ID2; TAF1D; MAFG; IFI16; ETS1; ARID5B; KLF6; ZNF23; BCL10; ATF3; ZNF880; PHF20; MAF; TOX; ENO1; FOSL1; ASH1L; ZNF281; FOS; MAFB; HEY1; MXD1; ZNF146; ZFX; ELK3; FOXO1; SFPQ; DNAJC2; NUP62; SAP18; NOC2L; MED21; DDX17; NACA; CAMTA2; CDK7; ZNF131; ADRB2; NPM1; EPC1; PNRC2; TRIM33; ATF4; MED10; ZBTB2; MLXIP; BRD7; ATF1; MED6; PURA; PURB; ZNF24; PAXBP1; CCDC59; TBX3; SNW1; MED1; FOSB; GABPB1; ASXL1; ARID3B; PSPC1; MED17; SNIP1; YY1; HNRNPD; GTF2I; AATF; JUN; KLF2; MAX; ZNF697; ZNF770; ZNF222; SUPT3H; HMGA2; TSC22D3; CHD7; EWSR1; NLK; NFIL3; CREB5; TSC22D1; CREM; SKIL; ZEB1; USF1; RBPJ; ARNTL2; PHF5A; BRD2; BCLAF1; MYC; ARL2BP; SAP30; THRAP3; ZNF800; ZNF267; CBX3; HLX; PRRX1; NFYB; TGIF1; ZNF354A; MED30; ZNF22; ZNF654; ID3; YAP1; DR1; KLF4; ZNF33A; ZNF174; RBBP5; SERTAD2; YBX3; SIRT7; GTF2A2; POLR3C; ZNF8; ZFP36L1; RNF6; ZFY; SUPT7L; ZNF37A; MLLT10; MYCL; HIRA; ZNF432; MED31; ZNF286A; UBE2I; ZNF789; PCGF5; STAT3; KLF5; RUNX1; ZBTB34; DDX54; NFYA; TAF1A; ZNF239; ZFP69B; BRF2; NR2C1; RBM39