Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00252	Penicillamine	E-MTAB-798	Hepatocyte	Human	24h	10000uM	EID0749

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	SOX6; TSHZ1; MAZ; TBL1X; ZNF618; TP53; ZBTB20; HIC2; CNOT3; JUND; CBX4; STAT6; SOX4; CREB3L3; IRF6; ATF5; SUPT6H; EGR1; MYRF; SOX5; USF2; ZBTB16; PEX14; NFKB2; EHMT2; NR1D2; ZIC1; ZBED3; ARHGAP35; CENPB; FLNA; ZNF292; TRAK1; ZNF57; ZFP36L2; PPARA; TRIM25; NR1H4; JUP; IRF2; ZNF791; HMG20B; HDAC5; PROX1; TCF19; NFIC; NR1D1; TADA3; PPARGC1A; HNF4A; MXI1; KAT2B; IRF3; PML; DBP; PDLIM1; CAPN15; ING1; RBPMS; HIPK1; REPIN1; RXRA; LPIN2; RARA; ZNF688; MEN1; TEAD2; PSIP1; DDX54; INSR; ERBB2; ZHX2; SMARCA4; CERS4; VGLL4; ZNF768; SSBP3; HDAC6; GTF2IRD1; CTBP1; BAZ2A; TLE1; ARID1A; KAT6A; LITAF; HIPK2; SMARCC2; ARID4A; FOXP4; ZNF512B; IRF7; TOB1; KLF16; PBX2; POLR2A; SREBF2; NFE2L1; AJUBA; AES; GLMP; NCOR2; TRIM29; SMAD3; HMGA1; ZBTB48; CUX1; EPAS1; SPEN; TONSL; MED26; GRHL1; CBX7; CTNNB1; TFE3; PHF12; TRIM11; IRF9; NFIA; PIAS1; CUX2; GATA4; CBX5; NR2F6; RORA; SATB1; MYBBP1A; CEBPA; ATOH8; SALL1; KMT2D; E2F1; MED15; BRD3; SSBP2; ZKSCAN1; ETV1; MTA1; HDAC4; TCF7L2; SOX13; PPARGC1B; DOT1L; NAB2; HLF
Down-regulation	126	LMCD1; ANKRD1; ARL2BP; IFI16; KLF6; BCL10; ENO1; TAF1D; ZEB1; ETS1; MAFF; ZNF529; NACA; RNF6; TOX; PPARD; SFPQ; CREM; HIPK3; MAFG; ZNF23; ZNF432; ZNF654; PAWR; ZNF880; PNRC2; ASH1L; SUMO1; ZNF561; RBM39; ZNF322; THRAP3; CDC5L; BCLAF1; DDX17; THAP2; ZNF770; ID2; GZF1; CBFB; YBX3; TRIM22; MED21; JUN; ZNF544; KLF7; STAT3; ZFY; ZNF274; ZNF2; PRMT2; THRB; ZNF655; ZFP36L1; ZNF697; ZNF211; TAF9B; PHF20; ZNF146; MYC; MED4; GTF2A2; SOX7; ID3; USF1; ZNF286A; ZNF24; MAFB; THAP6; ARID5B; GTF2I; NFKBIZ; NPM1; HNRNPD; ZFX; TXNIP; SUPT7L; ZNF480; ZFP69B; CTBP2; ZNF281; ZNF614; MED17; CDK2; DDIT3; ZNF302; ZNF8; ZNF234; ELK3; ZFP62; ZBTB6; ZBTB21; NOC2L; ZNF260; ZNF567; ZNF468; ZNF268; ZNF165; NFYA; ZNF720; ZNF200; ZNF131; PRRX1; ZNF354A; CHD2; BRD7; ZNF239; EPC1; HNF4G; ZNF140; AFF4; ZNF267; ZNF45; RB1; MIER1; ATF1; PCGF5; YY1; ASXL1; BLZF1; UBE2I; ZBTB41; ZNF253; PURB; ZBTB34; TAF1A