Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00240	Nicotinic acid	E-MTAB-798	Hepatocyte	Human	24h	10000uM	EID0737

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	CCNA2; SOX6; ETV1; ZIC1; HDAC6; TBL1X; NR1H4; ZNF618; CUX2; CENPF; ERBB2; ARHGAP35; GLMP; KAT2B; SATB1; AES; MYRF; ZBED3; IRF6; PROX1; ZBTB20; LPIN2; HMG20B; PTTG1; SOX5; STAT6; TRIM25; TCFL5; CDIP1; ZNF512B; MAGED1; TCF19; HDAC11; CRYM; PDLIM1; JUP; CREB3L3; TP53; PBX1; STAT4; PSIP1; TRIM22; BBX; CREBL2; MXI1; FLNA; SUPT6H; PHF19; NR1H3; CNOT3; NPAS2; PPARGC1A; FOXM1; MED12; HIPK2; INSR; ARID1A; CEBPA; SREBF2; RBPMS; USF2; TRRAP; THAP8; TCEA2; TLE1; NFIA; CALR; TAF10; NFIC; CREB3L2; SMARCB1; ATF5; IRF9; ZFP90; ZSCAN2; CBX5; SLC2A4RG; TFE3; RFX5; THAP4; CITED4; HMGB2; SMARCA2; ESR1; CBX4; CTNNB1; SMARCA1; TSHZ2; ZNF292; ZHX3; LITAF; EHMT2; MMS19; PPARA; ZNF219; ITGB3BP; EPAS1; DTX1; MBD3; AFF3; HLTF; KLF12; SALL1; MYBL2; ARRB1; JUND; TADA3; MED16; ZNF688; PAX8; ARNT; CUX1; ZKSCAN1; NR3C2; BAZ2B; SMARCA4; ATF6; SSBP2; SOX4; MTA1; FOXP4; CTBP1; TSHZ1; TCF3; MDM2; ZNF362; ZBTB16; PCGF3; HLF; CSDC2; IRF2; CBX7; ZNF12; SMAD2; MED24; PHF12; NCOR2; ATOH8; TEAD2; ZNF467; HMBOX1; NR1I3; BRCA1; MED15; NSD2; ZNF652; MEN1; E2F8; ZNF561; MAZ; TCF7L2; HNF4A; GATA4; REPIN1; FOXN3; ZSCAN18; PIAS1; TONSL; SMARCC2; PBX2; HDAC5; CERS4
Down-regulation	225	LMCD1; MAFF; ANKRD1; SRF; THAP2; BCL10; TOX; ID2; TAF1D; KLF6; KLF7; ZNF880; MED21; YY1; ATF1; FOS; IFI16; ATF3; RNF6; HNRNPD; ZNF281; ARL2BP; ZFY; PKNOX1; BCLAF1; ETS1; GTF2I; PNRC2; MAFG; PPARD; STAT3; ZNF131; PHF20; SAP18; ASH1L; NUP62; NOC2L; ZNF146; CDC5L; MED6; BAZ1A; TRIM33; ELK3; ENO1; ZNF770; ZFX; SFPQ; DDX17; PSPC1; ARNTL2; MEF2A; DNAJC2; GABPB1; ZNF22; ASXL1; ZBTB2; CBFB; NFYA; MXD1; ZNF267; KLF3; ZNF23; MAF; PAXBP1; ZBTB34; YAP1; ZNF174; SNW1; SRSF2; TTF1; CDK7; MED10; ZEB1; TSC22D1; RLIM; KLF4; NLK; TBPL1; MED17; MED30; ZNF24; RBM39; ZNF823; ZNF800; ETS2; PHIP; PURB; TERF2; POLR3C; ID3; BHLHE40; BASP1; SPEN; ZMYND11; ZNF654; HSF2; ZNF35; PRRX1; MAX; UBE2L3; HIPK3; ZNF639; ADRB2; FOXO1; GLIS3; SOX7; RB1; ARID5B; MYCL; MIER1; YAF2; NPM1; ZNF200; EPC1; UBE3A; ZNF670; MED1; ZNF655; ZFP69B; SETD2; RBPJ; PHF5A; BRD2; PCGF6; THRAP3; ZBTB44; USF1; ZNF614; SUPT7L; CHD1; HEY1; DR1; COPS2; SIRT7; UBE2I; THAP12; SERTAD2; PURA; GTF2A2; SOX9; E2F6; MYNN; SUV39H2; TFCP2; FOSL1; SAP30; NFYB; CREM; GZF1; ZNF562; TSC22D2; ING3; ETV3; TXNIP; ZNF567; ZNF432; ZNF3; TAF11; CCDC59; TAF1A; CRK; RUNX1; ARID3B; BACH1; PCGF5; RCOR3; RNF138; ZZZ3; PA2G4; TBX3; ZNF468; HES1; ZNF789; CHD2; BRF2; JUN; CNOT2; ZNF8; CREB1; MED4; ZNF26; MAFB; ZNF37A; EWSR1; MIER3; ZBTB24; ZNF268; ZNF33A; MLXIP; SUPT3H; NACA; FOXJ3; ZNF420; TAF9B; GABPA; ZNF195; HNF4G; RLF; SKIL; KLF5; MLLT10; IKZF5; GMEB1; ZNF222; SNIP1; ZNF573; ZNF398; ZNF354A; YBX3; ZNF2; BRWD1; KLF2; CREBZF; MED13; BRD7; ZNF33B; ZNF134; ZNF569; MED31; ZFP36L1; HMGA2; TEAD4; CTBP2; ZNF649; PAWR