Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00232	Mexiletine	E-MTAB-798	Hepatocyte	Human	24h	60uM	EID0729

Response Information :

Types	Number	Response transcription factors
Up-regulation	89	LMCD1; ANKRD1; ID2; TOX; MAFG; TXNIP; IFI16; MAFF; ATF3; MAF; BCL10; SRF; CREM; KLF6; ENO1; ZNF880; ETS1; KLF7; DDIT3; BCLAF1; THAP2; ZNF165; YBX3; ZNF654; JUN; PNRC2; ADRB2; MLXIP; FOS; ZNF697; PPARD; YY1; ID3; DDX17; BASP1; TRIM33; TAF1D; ARNTL2; DDX54; MXD1; ARID5B; NFKBIZ; MAFB; NFIL3; SFPQ; ZNF22; INSR; ETS2; ZHX1; ARID3B; PHF20; ZBTB43; ATF1; EPC1; ZNF432; MKX; ZFX; ASH1L; ATF2; MED30; ZFY; MED21; THRB; ZEB1; ZNF23; ZNF131; GABPB1; PCGF5; PRRX1; GZF1; ARL2BP; USF1; GTF2I; ZNF789; HNF4G; PRDM2; MED31; NACA; FOXO1; ZNF281; KLF2; STAT3; NOC2L; SAP30; ZNF211; TAF1A; ZNF573; ZNF655; PAWR
Down-regulation	122	REPIN1; SOX6; KAT2B; CITED2; ERBB2; ZNF618; TBL1X; ARHGAP35; CUX2; PROX1; TOB1; MYRF; ARID1A; NR1H4; TSHZ1; HMG20B; LPIN2; SSBP2; TP53; EPAS1; HLF; BBX; ZNF652; PLAGL1; JUND; SOX4; ZBTB20; ARRB1; RBM14; TFE3; HSF1; PPARA; FOXQ1; ZNF512B; HNF4A; MYBBP1A; PAX8; ZNF787; SOX5; AES; PDLIM1; MXI1; MAZ; IRF2; ZBTB16; SALL1; NR2F2; CITED4; ZBED3; STAT6; PML; FLNA; HIPK2; MED25; ZFHX3; CLOCK; TLE1; TAF5L; PSPC1; PSIP1; GLMP; CBX5; CTBP1; CCNA2; HDAC6; ZIC1; MED16; PURA; KMT2D; SUPT6H; JUP; NFIA; UBTF; EHMT1; OSR1; NFIC; AFF3; BRD3; SRCAP; TCF7L2; PIAS1; ATOH8; AJUBA; ARNT; ZNF367; MEN1; RXRA; NFKB2; ZNF292; RBPMS; TCF19; ETV1; SREBF2; CNOT3; SMARCA2; CTNNB1; GATA4; CBFA2T2; TRIM29; NFIB; TCFL5; ARID1B; SOX13; E2F8; IRF6; FOXN3; ETV5; CREB3L3; TRRAP; TEAD2; NFYB; PEX14; CERS4; KMT2C; L3MBTL2; ZNF12; PHF19; ZBTB47; NR5A2; ZBTB45; SLC2A4RG; PBX1