Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00173	Cimetidine	E-MTAB-798	Hepatocyte	Human	24h	60uM	EID0670

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	ID2; DDIT3; HEY2; TAF1D; ANKRD1; MAFF; TAF1A; SOX7; NR4A2; ZNF654; ATF3; ZNF131; ZNF3; CHD2; ZNF281; THAP2; PAWR; ARL2BP; FOXO1; NR0B2; ASH1L; ENO1; FOS; MED6; SFPQ; NOCT; MAFG; PHF20; KLF6; ELF3; NFIL3; ZNF550; BCL10; TOX3; SETD3; HES1; THRB; PTTG1; SMAD1; PURA; THRAP3; THAP6; DDX54; NOC2L; PCGF5; SAP18; RORA; SNIP1; HBP1; ZBTB21; TRIM33; PPARD; INSR; MED31; MIER1; HEY1; ZNF302; MAX; ZNF615; YY1; RBM39; UBE2I; TXNIP; ZNF836; ZNF2; USF3; JMY; ZNF141; ZNF222; DR1; USF1; GTF2I; ZNF84; MXD1; SOX4; SAP30; THAP5; ZNF432; PURB; ZNF420; NUP62; ZFP36L1; TMF1; ZNF555; JUN; GZF1; ZNF44; ZNF234; ZNF573; BRWD1
Down-regulation	127	ZNF512B; ARID1A; IRF9; TOB1; FLNA; NFIC; HIPK2; JUP; MED16; KMT2D; HIVEP1; CAVIN1; STAT6; ZBTB38; ZBTB20; NR1D2; REPIN1; IRF7; ATF5; TBL1X; CNOT3; ARID1B; ZBED3; ZNF618; CBX5; HNF4A; CLOCK; MXI1; GATA4; PPP1R13L; DDX17; TFE3; MYRF; KMT2C; TP53; MED14; EHMT1; BRD3; PLAGL1; MKX; CUX2; RBPMS; TRIM22; TADA3; NFKB2; BCL9L; ZBTB7A; ZNF407; SREBF2; TCFL5; ATF6; NR2F6; TBX1; MAZ; WWC1; ZNF655; CAPN15; ARHGAP35; WDR5; CUX1; TSHZ1; MED25; MED15; MECP2; AJUBA; ZNF787; ABL1; ZBTB45; BBX; TSHZ2; ZFP90; EP300; ZFP36L2; EPAS1; SOX6; RSF1; RXRA; SMARCA4; ZHX2; CREBL2; AES; KDM1B; TRIM25; TLE1; FHL2; SLC2A4RG; MAML3; CERS6; ZFAT; SMAD3; HDAC4; PPARA; FOXP4; ZKSCAN1; TRIM16; ERBB2; MTDH; SOX5; TCF7L2; GLIS3; DOT1L; TCF19; UBTF; ZNF292; SSBP3; CERS4; PROX1; BPTF; AFF3; ZNF561; GTF2IRD1; NFIA; GATAD2A; TRIM29; TEAD1; EHMT2; NCOR2; PBX1; BCL3; JUND; MLLT10; HIPK1; NCOA2; ZNF652; BAZ2A; SUPT6H; TRRAP