Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID00169	Chlorpheniramine	E-MTAB-798	Hepatocyte	Human	24h	90uM	EID0666

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	ATF3; ANKRD1; MAFF; DDIT3; THAP2; PAWR; MAFG; ELF3; NFIL3; ENO1; TAF1D; NOCT; THRAP3; HBP1; LMCD1; BLZF1; ARID3B; ZBTB43; CDC5L; CALR; PPARD; ZNF654; JUN; SFPQ; KLF6; ZFPM1; CCDC59; SOX15; ID2; IKZF1; PCGF5; NR1D1; BCLAF1; TCF15; FOXO4; RORA; BRF2; FOSL1; USF1; FOXO3; ZNF835; ATF4; ING2; NR1D2; FOXO1; HIF3A; RCOR2; ZNF581; SAP30; KLF16; NR0B2; RBM39; NR4A2; SERTAD2; NCOR2; ZNF646; KLF5; TGIF1; BHLHE40; L3MBTL1; MED30; LIN28A; BRD4; TFAP4; ETV4; ETS1; ZNF3; ZNF165; SRF; ZNF747; TRAF6; BTG1; KCNIP3; MYOG; ZNF574; EPC1; SETD3; KLF7; ZNF611; CHD2; ZNF771; MED10; MIER1; TSC22D1; RBAK; ATF2; RUNX3; ELOB; DNAJC2; PHF20; HES1; FOSB; KLF2; MDM2; TBX2; HOXB9; MXD1; UBE2I; ZBTB24; MNT; LEF1; ZNF513; FOS; MDFI; PATZ1; ZSCAN20; TRIB3; CEBPG; NACA; ZNF496; ZNF681; MAFK; ZFP36L1; CITED2; CDK9; PHF1; ING4; HEY2; MEF2D; DDX54; MSL3; TAF1A; FOXJ1; JMY; ZNF554; KMT2B; HMX1; OTP; KMT5A; ZNF552; ZBTB34; WNT4; BCL10; MAX; ZNF793; GLI3; EGR4; ZNF460; TSC22D2; ARL2BP; RUNX2; MLXIPL; RARG; TOX3; RLF; CIZ1; HMGB2; KLF11; PRDM2; MYCN; ARID5B; MED27; ZNF528
Down-regulation	385	SOX6; CBX5; PROX1; ZBTB44; BBX; KMT2D; TCFL5; FOXQ1; MTDH; ARHGAP35; HLF; TSHZ1; MAML3; HIPK2; TRIM22; ZNF512B; RBBP4; CREBL2; MRTFB; TRIM25; MAF; PURA; ATF6; TEAD1; SSBP2; CUX2; NFIC; TRIM16; ZFP90; SOX5; RNF14; RFX5; TBL1X; PRKDC; ZNF367; WWP1; ARID1A; NR1H4; SMARCA1; EHMT1; CERS6; MXI1; TFDP1; FLNA; ZNF260; KLF3; ELP1; AJUBA; FOXA1; MYBL1; ELK4; IRF2; KAT2B; KDM2A; PCGF3; AR; YY1; ZBED3; RBM14; HMGN3; ONECUT2; PMS1; NAB1; ZMYND8; RXRA; ZBTB20; ZSCAN29; HLTF; NCOR1; ZFHX3; MTF2; CNOT6; SMAD5; ZMYND11; ZKSCAN1; LPIN2; AGO2; NFIB; PSPC1; TBL1XR1; SALL1; ZBTB8A; ZBTB18; RSF1; ERBB2; SMARCA5; ZNF680; SUB1; ZBTB38; SSBP3; PHF12; TAF9B; NR2F2; ZBED1; KDM1B; STAT2; ZNF618; JAZF1; PHF19; ZKSCAN7; DNMT1; REPIN1; BDP1; SUZ12; TFAM; ITGB3BP; TOB1; DDX17; TCF3; GATA4; SMARCA2; KLF12; GLMP; SMARCA4; HNF4A; GLIS3; MYRF; ARNT; TRIM33; ZNF407; E2F8; AFF3; BTAF1; FOXN3; SNAI2; CREB1; CLOCK; ZNF180; TRIM32; TRRAP; RNF141; TFE3; ELP2; MDM4; VDR; NFIA; NSD2; THRB; CEBPD; PSIP1; RBPMS; ZMYM2; KMT2C; CBX6; ETV1; CCNE1; USF3; SLC2A4RG; HDAC3; CREBZF; SMARCC2; GMNN; PML; WWTR1; ZNF655; CREB3L2; ZNF641; NCOA2; DDX5; PIAS1; CAVIN1; ZNF322; RCOR1; ASH1L; NFE2L2; RRN3; RNF138; HMG20B; ZNF362; ZNF12; ASH2L; GATAD2A; CCNA2; WWC1; ZFX; ZHX2; BCOR; MLXIP; CBL; TAF4; PPARA; SMAD1; MED14; PARP1; PPARGC1B; IRF9; FOXP1; TGS1; IRF7; TTF2; JAK2; BPTF; ADNP; ZNF770; ORC2; CNOT1; CDYL; MEIS2; KLF9; ID1; RREB1; HHEX; STAT1; SMAD2; TFDP2; ZBTB14; MAFB; HMGB3; CHD9; PLAGL1; TCF19; RBBP8; STAT5B; ZNF558; KLF13; TLE1; NCOA3; FUBP1; TBX1; NR1H3; ZNF507; ZNF268; HIVEP1; SUV39H2; MED25; ARNTL2; MYSM1; UBE3A; NFATC3; C1D; ZSCAN32; LCOR; ZNF266; TAF6; EED; KMT2A; HMGB1; CCAR1; ZNF776; GRHL1; MED23; ZFP1; MAGED1; LIMD1; NR2C2; PLRG1; KCTD1; RFC1; ING5; KLF15; ZNF264; STAT3; NLK; ZNF33B; SP3; GTF3A; ADNP2; MTF1; NR3C1; ZNF468; TCF7L2; ZFP62; GTF2I; IRF6; AES; FOSL2; PCBD2; YAP1; BAZ2B; ARID4A; SMARCC1; BRCA2; ZFP69; TGFB1I1; UBE2B; HIPK3; RBFOX2; TERF1; ZNF678; SKI; ZNF33A; IKZF5; KDM5B; ZXDB; CTBP1; ZNF292; CHD4; MTA1; ZNF107; L3MBTL4; RBL2; TERF2; ZSCAN5A; PURB; JUP; SP1; MED24; PHF2; STAT6; MED1; ZNF652; ATF1; ZNF30; TMF1; EPAS1; KDM2B; RNF20; WDR5; MED13; ZNF485; ZXDC; NR1I2; SUPT6H; ZNF557; MEN1; BCL9L; RBL1; SMAD4; ZNF780A; BRIP1; SREBF2; WDHD1; VEZF1; PIR; E2F7; MED16; ZNF121; EHMT2; PIAS2; ABL1; EID2; NFYB; ZNF93; SMARCD1; RFX7; NPAT; ZNF559; ZNF148; ZNF721; ZNF45; ZNF684; MAZ; TSHZ2; CREB5; ZNF24; THAP6; ZNF124; ZBTB47; HIPK1; INSR; ZNF91; SATB2; ARRB1; ZNF846; ZNF587B; IRF1; MBD1; HMGXB4; PHIP; CHD7; ZNF561; HIRA; HDAC8; SP100; THAP10; CDK8; PEG3; ARID1B; ZNF138; NCOA1; ZHX1; HDAC4; URI1; EZH2; TCF12; PBX2; ZNF544; GABPA; EP300; HOXA7; PBX1; KDM5A; ZNF514; ING3; ZNF397