Targets of perturbagens

Perturbagen ID : CID57779

Perturbagen : (s)-(−)-nicotine; (s)-3-(1-methylpyrrolidin-2-yl)pyridine; (s)-3-(n-methylpyrrolidin-2-yl)pyridine; (s)-nicotine; (−)-nicotine; 3-(2-(n-methylpyrrolidinyl))pyridine; 3-(n-methylpyrollidino)pyridine; American fare nicotine transdermal system; Basic care nicotine; Berkley and jensen nicotine; Berkley and jensen nicotine polacrilex; Care one nicotine; Careone mini nicotine polacrilex; Careone nicotine; Careone nicotine polacrilex; Careone nicotine transdermal system step 1; Careone nicotine transdermal system step 2; Careone nicotine transdermal system step 3; Dg health nicotine; Equaline nicotine; Equate nicotine; Exchange select nicotine transdermal system step 3; Good neighbor pharmacy nicotine; Good neighbor pharmacy nicotine mini; Good sense nicotine; Good sense nicotine mint; Good sense nicotine stop smoking aid; Habitrol patch nicotine transdermal system, step 1; Habitrol patch nicotine transdermal system, step 2; Habitrol patch nicotine transdermal system, step 3; Harris teeter nicotine; Health mart nicotine; Health mart nicotine polacrilex; Healthmart nicotine transdermal system step 1; Healthmart nicotine transdermal system step 2; Healthmart nicotine transdermal system step 3; Healthy accents nicotine; Humana pharmacy nicotine; In control nicotine; Kirkland signature quit 2; Kirkland signature quit 4; Kroger nicotine transdermal system step 1; Kroger nicotine transdermal system step 2; Kroger nicotine transdermal system step 3; L(−)-nicotine; Leader nicotine; Leader nicotine transdermal system step 1; Leader nicotine transdermal system step 2; Leader nicotine transdermal system step 3; Meijer nicotine transdermal system step 1; Meijer nicotine transdermal system step 2; Meijer nicotine transdermal system step 3; Members mark mini nicotine; Members mark nicotine; Mini nicotine; Nicoderm cq; Nicorelief; Nicorette; Nicorette cinnamon surge; Nicorette fresh mint; Nicorette fruit chill; Nicorette invisipatch; Nicorette mint; Nicorette original; Nicorette spearmint burst; Nicorette white ice mint; Nicotine; Nicotine betadex; Nicotine coated mint; Nicotine gum; Nicotine mini; Nicotine mint flavor; Nicotine original; Nicotine polacrilex; Nicotine polacrilex coated fruit; Nicotine polacrilex coated mint; Nicotine polacrilex origianl flavor; Nicotine polacrilex original flavor; Nicotine polacrilex stop smoking aid; Nicotine polacrilex, coated fruit flavor; Nicotine polacrilex, coated mint flavor; Nicotine polacrilex, original; Nicotine stop smoking aid; Nicotine tartrate; Nicotine transdermal system; Nicotine transdermal system patch kit; Nicotine transdermal system step 1; Nicotine transdermal system step 2; Nicotine transdermal system step 3; Nicotine un1654; Nicotrol; Nicotrol (professional sample); Nictoine gum; Preferred plus nicotine; Preferred plus nicotine polacrilex gum, original flavor; Rexall nicotine; Rite aid nicotine transdermal system step 1; Rite aid nicotine transdermal system step 2; Rite aid nicotine transdermal system step 3; Rugby nicotine; Rugby nicotine polacrilex gum, coated cinnamon flavor; Rugby nicotine polacrilex gum, coated fruit flavor; Rugby nicotine polacrilex gum, coated mint flavor; Rugby nicotine polacrilex gum, mint flavor; Rugby nicotine polacrilex gum, original flavor; Safeway nicotine transdermal system step 1; Safeway nicotine transdermal system step 2; Safeway nicotine transdermal system step 3; Signature care nicotine; Simply right nicotine; Smart sense nicotine; Smart sense nicotine mint; Smart sense nicotine polacrilex; Stop smoking aid; Stop smoking aid nicotine; Sunmark nicotine; Sunmark nicotine transdermal system step 1; Sunmark nicotine transdermal system step 2; Sunmark nicotine transdermal system step 3; Topcare nicotine; Topcare nicotine gum; Topcare nicotine polacrilex; Topcare nicotine stop smoking aid; Tru relief nicotine; Up and up nicotine; Up and up nicotine polacrilex; Zonnic; Zonnic nicotine; Zonnic nicotine mini; Zonnic nicotine polacrilex

Target	Effect	Reference
ALAD	-1	STITCH
CYP1A2	-1	STITCH
CYP2A6	-1	STITCH
IL2	-1	STITCH
PON1	-1	STITCH
STAR	-1	STITCH
TNF	-1	STITCH
AKT1	1	STITCH
ALDH1A1	1	STITCH
AOX1	1	CLUE; STITCH
CASP3	1	STITCH
CHAT	1	CLUE; STITCH; DrugBank
CHRFAM7A	1	STITCH
CHRNA10	1	DrugBank; STITCH; CLUE
CHRNA2	1	DrugBank; STITCH; CLUE
CHRNA3	1	DrugBank; STITCH; CLUE
CHRNA4	1	DrugBank; STITCH; CLUE
CHRNA5	1	DrugBank; STITCH; CLUE
CHRNA6	1	DrugBank; STITCH; CLUE
CHRNA7	1	DrugBank; STITCH; CLUE
CHRNA9	1	DrugBank; STITCH; CLUE
CHRNB2	1	DrugBank; STITCH; CLUE
CHRNB3	1	DrugBank; STITCH; CLUE
CHRNB4	1	DrugBank; STITCH; CLUE
CYP19A1	1	CLUE; STITCH; DrugBank
CYP2A13	1	STITCH
CYP2A7	1	STITCH
CYP2B6	1	CLUE; STITCH
CYP2E1	1	STITCH
CYP2U1	1	STITCH
FGF2	1	STITCH
FOS	1	STITCH
FYN	1	STITCH
LCK	1	STITCH
MAPK1	1	STITCH
MAPK3	1	STITCH
MYC	1	STITCH
NFKB1	1	STITCH
PRKCA	1	STITCH
PRKCZ	1	STITCH
PTGS2	1	STITCH
RAF1	1	STITCH
SLC6A3	1	STITCH
SRC	1	STITCH
STAT3	1	STITCH
TBXAS1	1	CLUE; STITCH
TH	1	STITCH
TRPA1	1	CLUE; STITCH
VEGFA	1	STITCH
ACSL1	2	STITCH
ATP5F1E	2	STITCH
BAX	2	STITCH
BCL2	2	STITCH
BDNF	2	STITCH
CDS1	2	STITCH
CHRNA1	2	STITCH
CHRNB1	2	STITCH
CHRND	2	STITCH
CHRNE	2	STITCH
CHRNG	2	STITCH
CSF2	2	STITCH
CYCS	2	STITCH
CYP1A1	2	STITCH
CYP2S1	2	STITCH
CYP4X1	2	STITCH
EGFR	2	STITCH
FMO1	2	STITCH
FMO2	2	STITCH
FMO3	2	STITCH
FMO4	2	STITCH
FMO5	2	STITCH
GGCT	2	STITCH
GM2A	2	STITCH
GNAI2	2	STITCH
GPATCH2	2	STITCH
GPR50	2	STITCH
HSD17B7	2	STITCH
HTR3A	2	STITCH
HTR3B	2	STITCH
HTR3C	2	STITCH
HTR3D	2	STITCH
HTR3E	2	STITCH
ID2	2	STITCH
INMT	2	STITCH
LDLRAD3	2	STITCH
MAPK8	2	STITCH
MCL1	2	STITCH
MYOF	2	STITCH
NFE2L1	2	STITCH
PARP4	2	STITCH
PDGFB	2	STITCH
PNMT	2	STITCH
PRPS1	2	STITCH
RB1	2	STITCH
RND3	2	STITCH
RPS24	2	STITCH
SH3D19	2	STITCH
SNAI1	2	STITCH
STXBP5	2	STITCH
TENT4A	2	STITCH
TMEM222	2	STITCH
TRIM28	2	STITCH
UGT1A3	2	STITCH
UGT1A4	2	STITCH
UGT1A9	2	STITCH
UGT2B10	2	STITCH
UGT2B11	2	STITCH
ZC3H7A	2	STITCH