Targets of perturbagens

Perturbagen ID : CID57738

Perturbagen : 2,2-dimethylbutyric acid, 8-ester with (4r,6r)-6-(2-((1s,2s,6r,8s,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2h-pyran-2-one; Act simvastatin; Apo-simvastatin; Auro-simvastatin; Ava-simvastatin; Bci simvastatin; Dom-simvastatin; Ezetimibe and simvastatin; Flolipid; Ipg-simvastatin; Jamp-simvastatin; Mar-simvastatin; Mint-simvastatin; Mylan-simvastatin; Ntp-simvastatin; Nu-simvastatin tablets; Phl-simvastatin; Pms-simvastatin; Q-simvastatin; Ran-simvastatin; Ratio-simvastatin; Riva-simvastatin; Sandoz simvastatin; Septa-simvastatin; Simvastatin; Simvastatin tablets; Simvastatin-10; Simvastatin-20; Simvastatin-40; Simvastatin-80; Simvastatin-odan; Simvastatina; Simvastatine; Simvastatinum; Synvinolin; Taro-simvastatin; Teva-simvastatin; Vytorin; Zocor; Zym-simvastatin

Target	Effect	Reference
ABCB11	-1	STITCH
APP	-1	STITCH
CCL2	-1	STITCH
COG2	-1	STITCH
CXCL8	-1	STITCH
CYP2C8	-1	CLUE; STITCH
CYP3A4	-1	CLUE; STITCH
CYP3A5	-1	CLUE; STITCH
EDN1	-1	STITCH
F2	-1	STITCH
F3	-1	STITCH
HMGCR	-1	DrugBank; CLUE; STITCH
IL6	-1	STITCH
ITGAL	-1	DrugBank; STITCH
ITGB2	-1	CLUE; STITCH; DrugBank
MAPK1	-1	STITCH
MAPK3	-1	STITCH
MMP1	-1	STITCH
MMP9	-1	STITCH
NPC1L1	-1	DrugBank
PDGFB	-1	STITCH
PTK2	-1	STITCH
RAC1	-1	STITCH
RAF1	-1	STITCH
SERPINE1	-1	STITCH
SLCO1B1	-1	STITCH
SOAT1	-1	DrugBank
STAT1	-1	STITCH
STAT3	-1	STITCH
TNF	-1	STITCH
ABCB1	1	STITCH
AKT1	1	STITCH
APOB	1	STITCH
ATM	1	STITCH
BMP2	1	STITCH
BMPR2	1	STITCH
CASP12	1	STITCH
CASP3	1	STITCH
CASP6	1	STITCH
CASP7	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CAT	1	STITCH
FDFT1	1	STITCH
HMOX1	1	STITCH
IL1B	1	STITCH
LDLR	1	STITCH
MMP2	1	STITCH
NFKB1	1	STITCH
NR1I2	1	STITCH
NR1I3	1	STITCH
PLAT	1	STITCH
PON1	1	STITCH
RELA	1	STITCH
RHOA	1	STITCH
SLC6A4	1	STITCH
TP53	1	STITCH
VEGFA	1	STITCH
ABCC3	2	STITCH
ANPEP	2	DrugBank
APOA1	2	STITCH
APOE	2	STITCH
BAD	2	STITCH
BGLAP	2	STITCH
CHUK	2	STITCH
COL13A1	2	STITCH
CYP3A7	2	STITCH
EAF2	2	STITCH
FOS	2	STITCH
FOXO1	2	STITCH
H2AFX	2	STITCH
H2AX	2	STITCH
HRAS	2	STITCH
IFNG	2	STITCH
IKBKB	2	STITCH
IL17A	2	STITCH
IL17F	2	STITCH
IL21	2	STITCH
IL22	2	STITCH
IL27	2	STITCH
IL4	2	STITCH
JUN	2	STITCH
KRAS	2	STITCH
MRPS31	2	STITCH
NFATC3	2	STITCH
NFKBIA	2	STITCH
NRP1	2	STITCH
PARP1	2	STITCH
RAP1A	2	STITCH
RB1	2	STITCH
SREBF1	2	STITCH
TNFSF10	2	STITCH