Targets of perturbagens

Perturbagen ID : CID57619

Perturbagen : Biotecan; Camptosar; Camptosar injection; Camptothecin-11; Irinotecan; Irinotecan for injection; Irinotecan hydrochloride; Irinotecan hydrochloride injection; Irinotecan hydrochloride injection, usp; Irinotecan hydrochloride trihydrate for injection; Irinotecan hydrochloride trihydrate injection; Onivyde

Target	Effect	Reference
CYP3A4	-1	STITCH
CYP3A5	-1	CLUE; STITCH
TOP1	-1	DrugBank; CLUE; STITCH
TOP1MT	-1	DrugBank; CLUE; STITCH
TOP2A	-1	STITCH
TYMS	-1	STITCH
UGT1A1	-1	STITCH
UGT1A10	-1	STITCH
CASP3	1	STITCH
CASP8	1	STITCH
CASP9	1	STITCH
CES2	1	STITCH
CHEK1	1	STITCH
EGFR	1	STITCH
HES1	1	STITCH
MAPK1	1	STITCH
MAPK3	1	STITCH
NFKB1	1	STITCH
RELA	1	STITCH
TNFSF10	1	STITCH
TP53	1	STITCH
ABCB1	2	STITCH
ABCC1	2	STITCH
ABCC2	2	STITCH
ABCG2	2	STITCH
ACAT1	2	STITCH
ACHE	2	STITCH
AK2	2	STITCH
ATM	2	STITCH
ATP2B4	2	STITCH
ATP6V0B	2	STITCH
ATP7A	2	STITCH
CCN1	2	STITCH
CCNB1IP1	2	STITCH
CCNB2	2	STITCH
CDC20	2	STITCH
CEL	2	STITCH
CES1	2	STITCH
CES3	2	STITCH
CES5A	2	STITCH
CHEK2	2	STITCH
COL7A1	2	STITCH
CYP3A7	2	STITCH
CYR61	2	STITCH
DBF4	2	STITCH
DFFB	2	STITCH
DPYD	2	STITCH
IL6	2	STITCH
ITGAE	2	STITCH
LSM7	2	STITCH
MCL1	2	STITCH
MGMT	2	STITCH
MYB	2	STITCH
NDRG1	2	STITCH
NFKBIA	2	STITCH
NR3C1	2	STITCH
ORC1	2	STITCH
OSMR	2	STITCH
PBXIP1	2	STITCH
PLPP1	2	STITCH
POLA1	2	STITCH
POLE2	2	STITCH
POLR3G	2	STITCH
POR	2	STITCH
PRKCA	2	STITCH
PRKCB	2	STITCH
PRKCD	2	STITCH
PRKCI	2	STITCH
PRKDC	2	STITCH
PSAT1	2	STITCH
RBMS1	2	STITCH
RFC3	2	STITCH
RNF34	2	STITCH
SAT1	2	STITCH
SKP2	2	STITCH
SNRPF	2	STITCH
SP1	2	STITCH
STAT1	2	STITCH
TGFA	2	STITCH
THBS1	2	STITCH
UGT1A6	2	STITCH
UGT1A7	2	STITCH
UGT1A8	2	STITCH
UGT1A9	2	STITCH